1. Açık Erişim@BUU
  2. İndeksli Yayınlar
  3. Web of Science
Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/20892
Title: Clinical value of a mucin-like carcinoma-associated antigen in monitoring breast cancer patients in comparison with CA 15-3
Authors: Miserez, Andre R.
Müllerbrand, Jan
Walther, Eike
Fridrich, Raimund
Mäcke, Helmut
Uludağ Üniversitesi/Tıp Fakültesi/Nükleer Tıp Anabilim Dalı.
Güneş, İlknur
Keywords: Monoclonal-antibodies
CA 15-3
Tumor-markers
Disease
Diagnosis
Epitopes
MCA
Oncology
Issue Date: 1991
Publisher: Pergamon-Elsevier Science
Citation: Miserez, A. R. vd. (1991). ''Clinical value of a mucin-like carcinoma-associated antigen in monitoring breast cancer patients in comparison with CA 15-3''. European Journal of Cancer, 27(2), 126-131.
Abstract: A new tumour marker, mucin-like carcinoma-associated antigen (MCA), was evaluated in 176 breast cancer patients classified either as free of tumour (NED, n = 141) or as having metastases (PD, n = 35). During the 5 year follow-up, 842 measurements of MCA and 363 measurements of CA 15-3 were done. MCA levels were significantly increased in the PD group (P = 0.0001) but not in the NED group. The sensitivities of the MCA and the CA 15-3 assays were 84% and 78% and the specificities were 81% and 78%, respectively. The negative predictive value of 97% for MCA was significantly higher (P = 0.0001) than the 88% for CA 15-3. Thus the MCA enzyme immunoassay is at least equivalent to the CA 15-3 test and is recommended in the assessment of metastatic spread or tumour recurrence in breast cancer patients.
URI: https://doi.org/10.1016/0277-5379(91)90468-S
http://hdl.handle.net/11452/20892
ISSN: 0959-8049
Appears in Collections:Web of Science

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