Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/21327
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dc.date.accessioned2021-07-30T05:38:13Z-
dc.date.available2021-07-30T05:38:13Z-
dc.date.issued2005-09-
dc.identifier.citationYilmazlar, S. vd. (2005). "Medial portion of the cavernous sinus: Quantitative analysis of the medial wall". Clinical Anatomy, 18(6), 416-422.en_US
dc.identifier.issn0897-3806-
dc.identifier.urihttps://doi.org/10.1002/ca.20160-
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/ca.20160-
dc.identifier.urihttp://hdl.handle.net/11452/21327-
dc.description.abstractPituitary tumors invade the cavernous sinus via the medial wall. Researchers have speculated that this wall is composed of dura and that substances secreted by tumors might damage this barrier. In contrast to the lateral wall, little is known about the structure of the medial wall of the cavernous sinus (MWCS). This study provides the first detailed quantitative (thickness) and qualitative (histological) assessment of the MWCS. Eighteen sellar-parasellar tissue blocks were obtained from adult human autopsies. Ten specimens were used for microsurgical dissection and macroscopic anatomical description. Eight specimens were used for histopathological study and for recording computer measurements of MWCS thickness. Each of these eight specimens was divided into three approximately equal-sized pieces, with cuts made in the coronal plane from posterior to anterior starting at the anterior level of the pituitary stalk. Wall thicknesses were compared in the three different regions (posterior, middle, anterior), and also on the left vs. the right sides. The investigations showed that the MWCS is a distinct dural layer that forms a barrier between the medial venous space of the cavernous sinus and the pituitary gland. The mean thickness of the 48 total (left and right) MWCS observed in the 24 sections examined was 0.195 +/- 0.066 mm (range = 0.080-0.387 mm). This wall is composed of loosely arranged collagen fibers that comprise a specific layer known as "meningeal dura." The posterior third of the MWCS was significantly thinner than the middle third (P = 0.0014) or anterior third (P = 0.0001). No macro- or microscopic defects were observed in any of the MWCS in the 18 specimens. The thinness of the posterior MWCS suggests that this is the most likely path for extension of pituitary tumors into the cavernous sinus.en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnatomyen_US
dc.subjectTranssphenoidal approachen_US
dc.subjectPituitaryen_US
dc.subjectCavernous sinusen_US
dc.subjectMedial wallen_US
dc.subjectPituitary capsuleen_US
dc.subjectPituitary-adenomasen_US
dc.subjectSurgeryen_US
dc.subjectDural invasionen_US
dc.subjectTumorsen_US
dc.subjectCompartmenten_US
dc.subjectSpaceen_US
dc.subjectGlanden_US
dc.subjectAnatomy & morphologyen_US
dc.subject.meshCavernous Sinusen_US
dc.subject.meshDura Materen_US
dc.subject.meshHumansen_US
dc.subject.meshMicrodissectionen_US
dc.subject.meshPituitary Glanden_US
dc.subject.meshSella Turcicaen_US
dc.titleMedial portion of the cavernous sinus: Quantitative analysis of the medial wallen_US
dc.typeArticleen_US
dc.identifier.wos000231614600004tr_TR
dc.identifier.scopus2-s2.0-24644452497tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Nöroşirürji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-3633-7919tr_TR
dc.identifier.startpage416tr_TR
dc.identifier.endpage422tr_TR
dc.identifier.volume18tr_TR
dc.identifier.issue6tr_TR
dc.relation.journalClinical anatomyen_US
dc.contributor.buuauthorYılmazlar, Selçuk-
dc.contributor.buuauthorKocaeli, Hasan-
dc.contributor.buuauthorAydıner, Fatma-
dc.contributor.buuauthorKorfalı, Ender-
dc.contributor.researcheridAAH-5070-2021tr_TR
dc.identifier.pubmed16015624tr_TR
dc.subject.wosAnatomy & morphologyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ4en_US
dc.contributor.scopusid6603059483tr_TR
dc.contributor.scopusid6603500567tr_TR
dc.contributor.scopusid6504076503tr_TR
dc.contributor.scopusid7004641343tr_TR
dc.subject.scopusPituitary Neoplasms; Radiosurgery; Acromegalyen_US
dc.subject.emtreeCollagen fiberen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeCancer invasionen_US
dc.subject.emtreeCavernous sinusen_US
dc.subject.emtreeCavernous sinus medial wallen_US
dc.subject.emtreeComputer analysisen_US
dc.subject.emtreeDura materen_US
dc.subject.emtreeHistologyen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHuman tissueen_US
dc.subject.emtreeHypophysis capsuleen_US
dc.subject.emtreeHypophysis tumoren_US
dc.subject.emtreeMicrodissectionen_US
dc.subject.emtreeQualitative analysisen_US
dc.subject.emtreeQuantitative analysisen_US
dc.subject.emtreeThicknessen_US
dc.subject.emtreeTranssphenoidal hypophysectomyen_US
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