Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/22889
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dc.contributor.authorÖztürk, Ayşen Sevgi-
dc.date.accessioned2021-11-30T11:23:31Z-
dc.date.available2021-11-30T11:23:31Z-
dc.date.issued2009-02-
dc.identifier.citationÖztürk, A.S. vd. (2009). "Evaluating quality of life and pulmonary function of long-term survivors of non-small cell lung cancer treated with radical or postoperative radiotherapy". American Journal of Clinical Oncology-Cancer Clinical Trials, 32(1), 65-72.en_US
dc.identifier.issn0277-3732-
dc.identifier.urihttps://doi.org/10.1097/COC.0b013e31817e6ec2-
dc.identifier.urihttps://journals.lww.com/amjclinicaloncology/Fulltext/2009/02000/Evaluating_Quality_of_Life_and_Pulmonary_Function.14.aspx-
dc.identifier.urihttp://hdl.handle.net/11452/22889-
dc.description.abstractBackground: Our aim in the present study was to describe the quality of life (QOL), evaluate pulmonary function, and compare demographic and clinical characteristics with QOL in long-term survivors of non-small cell lung cancer treated with radical or postoperative radiotherapy. Methods: Twenty-eight patients were recruited in the study. QOL was evaluated using The European Organization for Research and Treatment of Cancer, Quality of Life Core Questionnaire (EORTC QLQ-C30, v.3). Statistical analysis was performed by SPSS 14. Results: Patients' files were reviewed in October 2006. Median duration of follow-up was 46 months (range: 25-125 months). Seven of 9 scales were found to meet the minimal reliability limit (Cronbach's alpha >0.70). The lowest and highest reliability coefficients were 0.56 and 0.93 for social and role functioning, respectively. All interscale correlations were statistically significant (P < 0.01). The strongest positive correlation was found between physical functioning and, role and cognitive functioning (r = 0.59, r = 0.37 or P = 0.01, P = 0.05, respectively). The highest correlation of EORTC QLQ-C30 and the Katnofsky performance scale (KPS) during the questionnaire was found to be with physical functioning and constipation (r = 0.41. r = 0.44 or P = 0.02, P = 0.01, respectively). When the effect of various demographic and clinical parameters on QOL was evaluated; initial KPS, age, educational level, health insurance status, stage, chemotherapy, comorbid disease, and passive smoking were determined as significant factors influencing QOL. Physical, role, cognitive, and emotional functions were found to be significantly lower in the presence of dyspnea (r = 0.42, r = 0.58, r = 0.50, r = 0.63 or P = 0.02, P < 0.01, P < 0.01, P < 0.05, respectively). Regarding the symptom scales, dyspnea was found to be correlated with increasing of fatigue, pain, insomnia, and appetite loss (r = 0.52, r = 0.40, r = 0.64, r = 0.38 or P < 0.01, P = 0.03, P < 0.05, P = 0.04, respectively). The parameters of pulmonary function tests (FEV1, FVC, and FEV1/FVC) did not show any significant relation with any scale of QOL. Conclusion: Overall, we found that QOL of our patients who survived at least 2 years after radiotherapy, was good. The Turkish version of the EORTC QLQ-C30, v.3 is a valid and reliable instrument for Turkish lung cancer patients and can be used in clinical studies. We believe further studies are needed to have a better understanding of patients' pretreatment and posttreatment .en_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectLong-term survivoren_US
dc.subjectNon-small cell lung canceren_US
dc.subjectPulmonary functionen_US
dc.subjectQuality of lifeen_US
dc.subjectRadiotherapyen_US
dc.subjectEuropean-organizationen_US
dc.subjectRespiratory symptomsen_US
dc.subjectBreast-canceren_US
dc.subjectEortc qlq-c30en_US
dc.subjectEx-smokersen_US
dc.subjectFollow-upen_US
dc.subjectQuestionnaireen_US
dc.subjectReliabilityen_US
dc.subjectValidityen_US
dc.subjectDyspneaen_US
dc.subjectOncologyen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCarcinoma, non-small-cell lungen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshLungen_US
dc.subject.meshLung neoplasmsen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNeoplasm recurrence, localen_US
dc.subject.meshPostoperative perioden_US
dc.subject.meshPrognosisen_US
dc.subject.meshProspective studiesen_US
dc.subject.meshQuality of lifeen_US
dc.subject.meshQuestionnairesen_US
dc.subject.meshRespiratory function testsen_US
dc.subject.meshSurvival rateen_US
dc.subject.meshSurvivorsen_US
dc.titleEvaluating quality of life and pulmonary function of long-term survivors of non-small cell lung cancer treated with radical or postoperative radiotherapyen_US
dc.typeArticleen_US
dc.identifier.wos000263190300014tr_TR
dc.identifier.scopus2-s2.0-60549109128tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-9027-1132tr_TR
dc.contributor.orcid0000-0002-2382-290Xtr_TR
dc.identifier.startpage65tr_TR
dc.identifier.endpage72tr_TR
dc.identifier.volume32tr_TR
dc.identifier.issue1tr_TR
dc.relation.journalAmerican Journal of Clinical Oncology-Cancer Clinical Trialsen_US
dc.contributor.buuauthorSarıhan, Süreyya-
dc.contributor.buuauthorErcan, İlker-
dc.contributor.buuauthorKaradağ, Mehmet-
dc.contributor.researcheridAAH-4970-2021tr_TR
dc.contributor.researcheridAAG-8744-2021tr_TR
dc.relation.collaborationYurt içitr_TR
dc.identifier.pubmed19194128tr_TR
dc.subject.wosOncologyen_US
dc.indexed.wosSCIEen_US
dc.indexed.wosSSCIen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid56404684500tr_TR
dc.contributor.scopusid6603789069tr_TR
dc.contributor.scopusid6601970351tr_TR
dc.subject.scopusResearch Management; Quality of Life; Patient-Reported Outcomeen_US
dc.subject.emtreeCarboplatinen_US
dc.subject.emtreeCisplatinen_US
dc.subject.emtreeEtoposideen_US
dc.subject.emtreeGemcitabineen_US
dc.subject.emtreePaclitaxelen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeen_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAnorexiaen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCancer chemotherapyen_US
dc.subject.emtreeCancer radiotherapyen_US
dc.subject.emtreeCancer stagingen_US
dc.subject.emtreeCancer survivalen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeCognitionen_US
dc.subject.emtreeComorbidityen_US
dc.subject.emtreeComparative studyen_US
dc.subject.emtreeConstipationen_US
dc.subject.emtreeCorrelation analysisen_US
dc.subject.emtreeCronbach alpha coefficienten_US
dc.subject.emtreeDyspneaen_US
dc.subject.emtreeEducationen_US
dc.subject.emtreeEmotionalityen_US
dc.subject.emtreeFatigueen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeForced expiratory volumeen_US
dc.subject.emtreeFunctional assessmenten_US
dc.subject.emtreeHealth insuranceen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeInsomniaen_US
dc.subject.emtreeKarnofsky performance statusen_US
dc.subject.emtreeLung functionen_US
dc.subject.emtreeLung function testen_US
dc.subject.emtreeLung small cell canceren_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical record reviewen_US
dc.subject.emtreePainen_US
dc.subject.emtreePassive smokingen_US
dc.subject.emtreePostoperative careen_US
dc.subject.emtreeQuality of lifeen_US
dc.subject.emtreeQuestionnaireen_US
dc.subject.emtreeReliabilityen_US
dc.subject.emtreeSocial statusen_US
dc.subject.emtreeStatistical analysisen_US
dc.subject.emtreeStatistical significanceen_US
dc.subject.emtreeSurvival timeten_US
dc.subject.emtreeEvaluationen_US
dc.subject.emtreeLungen_US
dc.subject.emtreeLung non small cell canceren_US
dc.subject.emtreeLung tumoren_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreePathophysiologyen_US
dc.subject.emtreePostoperative perioden_US
dc.subject.emtreePrognosisen_US
dc.subject.emtreeProspective studyen_US
dc.subject.emtreeQuality of lifeen_US
dc.subject.emtreeSurvival rateen_US
dc.subject.emtreeSurvivoren_US
dc.subject.emtreeTumor recurrenceen_US
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