Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/23169
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dc.date.accessioned2021-12-10T10:37:07Z-
dc.date.available2021-12-10T10:37:07Z-
dc.date.issued2012-08-11-
dc.identifier.citationCengiz, M. vd. (2012). "Molecular characterisation of quinolone resistance in Escherichia coli from animals in Turkey". Veterinary Record, 171(6), 155-155.en_US
dc.identifier.issn0042-4900-
dc.identifier.issn2042-7670-
dc.identifier.urihttps://doi.org/10.1136/vr.100719-
dc.identifier.urihttps://bvajournals.onlinelibrary.wiley.com/doi/full/10.1136/vr.100719-
dc.identifier.urihttp://hdl.handle.net/11452/23169-
dc.description.abstractThe aim of this study were to detect the gyrA, parC and marR mutations and qnr genes (qnrA, qnrB and qnrS) in 120 strains of Escherichia coli isolated from animals. European Committee on Antimicrobial Susceptibility Testing and Clinical Laboratory Standards Institute disc diffusion and minimum inhibitory concentration (MIC) tests, respectively, were used to determine fluoroquinolone (FQ) resistance, and molecular methods were used to detect the mutations and the genes. E coli isolates with an MIC of >= 8 mg/l had mutation at Ser-80 in parC in addition to mutations at Ser-83, Asp-87 or both in gyrA. The nucleotide change was detected in marR (Ser-3 -> Asn, Ala-53 -> Glu, Gly-103 -> Ser, Tyr-137 -> His). Only four E coli isolates (3.3 per cent) contained qnrA and qnrS, and qnrB was not detected. Two E coli isolates from healthy calves also contained qnrA and qnrS. The MICs of enrofloxacin and danofloxacin for qnr-containing E coli isolates ranged from 32 mg/l to 256 mg/l. The results of this study indicated that the FQ-resistant E coli isolates presented an alteration in gyrA (Ser-83 -> Leu, Asp-87 -> Asn) and parC (Ser-80 -> Ile) with high MICs (8-256 mg/l), and there was a low prevalence of qnr genes among E coli isolated from animals.en_US
dc.description.sponsorshipEuropean Cooperation in Science and Technology (COST) - BM0701en_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVeterinary sciencesen_US
dc.subjectFluoroquinolone-resistanceen_US
dc.subjectSalmonella-entericaen_US
dc.subjectKlebsiella-pneumoniaeen_US
dc.subjectQnr genesen_US
dc.subjectMechanismsen_US
dc.subjectEnterobacteriaceaeen_US
dc.subjectPrevalenceen_US
dc.subjectStrainsen_US
dc.subjectDeterminantsen_US
dc.subjectGyraseen_US
dc.subject.meshAnimalsen_US
dc.subject.meshAnti-bacterial agentsen_US
dc.subject.meshCattleen_US
dc.subject.meshCattle diseasesen_US
dc.subject.meshDose-response relationship, drugen_US
dc.subject.meshDrug resistance, bacterialen_US
dc.subject.meshEscherichia colien_US
dc.subject.meshEscherichia coli Infectionsen_US
dc.subject.meshMicrobial sensitivity testsen_US
dc.subject.meshMutationen_US
dc.subject.meshQuinolonesen_US
dc.subject.meshTurkeyen_US
dc.titleMolecular characterisation of quinolone resistance in Escherichia coli from animals in Turkeyen_US
dc.typeArticleen_US
dc.identifier.wos000308002200020tr_TR
dc.identifier.scopus2-s2.0-84865329442tr_TR
dc.relation.tubitakTOVAG-110O478tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Farmakoloji ve Toksikoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Mikrobiyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Sağlık Bilimleri Enstitüsü.tr_TR
dc.relation.bapUAP(V)-2009/11tr_TR
dc.contributor.orcid0000-0002-2245-5781tr_TR
dc.contributor.orcid0000-0001-9018-1842tr_TR
dc.contributor.orcid0000-0003-4337-577Xtr_TR
dc.contributor.orcid0000-0002-9212-8743tr_TR
dc.contributor.orcid0000-0002-0455-8736tr_TR
dc.identifier.startpage155tr_TR
dc.identifier.endpage155tr_TR
dc.identifier.volume171tr_TR
dc.identifier.issue6tr_TR
dc.relation.journalVeterinary Recorden_US
dc.contributor.buuauthorCengiz, Murat-
dc.contributor.buuauthorBüyükcangaz, Esra K.-
dc.contributor.buuauthorArslan, Erdem-
dc.contributor.buuauthorMat, Burak-
dc.contributor.buuauthorŞahintürk, Pınar-
dc.contributor.buuauthorSonal, Songül-
dc.contributor.buuauthorGöçmen, Hüban-
dc.contributor.buuauthorŞen, Ayşin-
dc.contributor.researcheridAAX-7249-2021tr_TR
dc.contributor.researcheridB-9095-2018tr_TR
dc.contributor.researcheridABE-5935-2020tr_TR
dc.contributor.researcheridABI-4237-2020tr_TR
dc.contributor.researcheridAAL-2323-2020tr_TR
dc.contributor.researcheridAAH-1820-2021tr_TR
dc.contributor.researcheridK-3299-2019tr_TR
dc.contributor.researcheridD-1599-2019tr_TR
dc.identifier.pubmed22890400tr_TR
dc.subject.wosVeterinary sciencesen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ1en_US
dc.contributor.scopusid16635026700tr_TR
dc.contributor.scopusid25649139400tr_TR
dc.contributor.scopusid55236738400tr_TR
dc.contributor.scopusid55342669100tr_TR
dc.contributor.scopusid55342852700tr_TR
dc.contributor.scopusid7801642676tr_TR
dc.contributor.scopusid56414715500tr_TR
dc.contributor.scopusid7401592869tr_TR
dc.subject.scopusQuinolones; Plasmids; Enterobacteriaceaeen_US
dc.subject.emtreeAntiinfective agenten_US
dc.subject.emtreeQuinolone derivativeen_US
dc.subject.emtreeAnimalen_US
dc.subject.emtreeAnimal diseaseen_US
dc.subject.emtreeAntibiotic resistanceen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCattleen_US
dc.subject.emtreeCattle diseaseen_US
dc.subject.emtreeDose responseen_US
dc.subject.emtreeDrug effecten_US
dc.subject.emtreeEscherichia colien_US
dc.subject.emtreeEscherichia coli infectionen_US
dc.subject.emtreeGeneticsen_US
dc.subject.emtreeMicrobiological examinationen_US
dc.subject.emtreeMicrobiologyen_US
dc.subject.emtreeMutationen_US
dc.subject.emtreeTurkey (republic)en_US
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