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Başlık: Primary small cell carcinoma of the breast: Report of seven cases and review of the literature
Yazarlar: Kılıçkap, Saadetin
Korkmaz, Taner
Öven, Bala Başak Ustaalıoğlu
Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Onkoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.
0000-0002-9732-5340
Kanat, Özkan
Canhoroz, Mustafa
Çubukçu, Erdem
Tolunay, Şahsine
Evrensel, Türkkan
Manavoğlu, Osman
AAI-1612-2021
AAJ-1027-2021
55881548500
52663246200
53986153800
6602604390
6603942124
6602587152
Anahtar kelimeler: Oncology
Breast
Chemotherapy
Radiotherapy
Small cell carcinoma
Surgery
Needle aspiration cytology
Neuroendocrine carcinoma
Yayın Tarihi: Tem-2011
Yayıncı: Sage Publications
Atıf: Kanat, O. vd. (2011). "Primary small cell carcinoma of the breast: Report of seven cases and review of the literature". Tumori Journal, 97(4), 473-478.
Özet: Aims and background. The aim of the study was to analyze the clinicopathological characteristics, treatment modalities, and clinical outcome of patients with primary small cell carcinoma of the breast. Methods. Fifty-three cases of primary small cell carcinoma of the breast were identified; 7 cases in this series and 46 from the English-language medical literature. Results. There were 52 females and 1 male. The mean age was 53 years. Tumor size ranged from 1 to 18 cm (mean, 4.53). Axillary node metastasis was present in 61.7%. Only one patient had distant metastases at presentation. The presence of hormone receptors was reported in 24.5% of the tumors. Modified radical mastectomy was the most common surgical procedure and was performed in 50.9% of the patients. Adjuvant radiotherapy was administered to 39.6% of the patients, and 69.8% underwent chemotherapy. Thirteen percent of patients received adjuvant tamoxifen therapy. The mean follow-up was 20.75 months (range, 3-60), and 10 of 53 cases (18.9%) died of metastatic disease. Conclusions. The prognosis of primary small cell carcinoma of the breast largely depends on the initial stage of the disease. Multimodality treatment including surgery, radiotherapy and chemotherapy seems to be the most appropriate strategy for early disease. Chemotherapy is usually unsuccessful in treating metastatic disease.
URI: https://doi.org/10.1177/030089161109700410
https://journals.sagepub.com/doi/abs/10.1177/030089161109700410
http://hdl.handle.net/11452/23730
ISSN: 0300-8916
2038-2529
Koleksiyonlarda Görünür:Scopus
Web of Science

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