Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/24722
Title: Distribution of COPD-related symptoms in the Middle East and North Africa: Results of the BREATHE study
Authors: Tageldin, Mohamed Awad
Nafti, Salim
Khan, Javaid Ahmed
Nejjari, Chakib
Beji, Majed
Mahboub, Bassam
Obeidat, Nathir M.
Sayıner, Abdullah
Wali, Siraj
Rashid, Nauman
El Hasnaoui, Abdelkader
Uludağ Üniversitesi/Tıp Fakültesi.
Uzaslan, Esra
AAI-1004-2021
8761653500
Keywords: Cardiovascular system & cardiology
Respiratory system
Copd
Middle east
Symptoms
North Africa
Breathe study
Prevalence
Chronic bronchitis
Smoking
Obstructive pulmonary-disease
Chronic-bronchitis
Lung-disease
Burden
Prevention
Prevalence
Management
Countries
Impact
Issue Date: Dec-2012
Publisher: W B Saunders
Citation: Tageldin, M. A. vd. (2012). "Distribution of COPD-related symptoms in the Middle East and North Africa: Results of the BREATHE study". Respiratory Medicine, 106, Supplement 2, S25-S32.
Abstract: Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. However, its epidemiology in many developing countries is poorly characterised. The objective of this analysis was to evaluate respiratory symptoms which could be COPD-related in a large sample of individuals aged 40 years in ten countries in the Middle East and North Africa (Algeria, Egypt, Jordan, Lebanon, Morocco, Saudi Arabia, Syria, Tunisia, Turkey and United Arab Emirates), together with Pakistan, using a standardised methodology. A random sample of 457,258 telephone numbers was contacted. A screening questionnaire was administered to each eligible participant, which included six questions relating to respiratory symptoms. Of 65,154 eligible subjects, 62,086 agreed to participate and 61,551 provided usable data. The age- and gender-adjusted prevalence of symptoms (persistent productive cough or breathlessness or both) was 14.3% [95% CI: 14.0-14.6%], ranging from 7.2% in UAE to 19.1% in Algeria. Symptoms were more frequent (p < 0.0001) in women (16.7%) than in men (12.2%). The adjusted prevalence of COPD according to the "epidemiological" definition (symptoms or diagnosis and cigarette use >= 10 pack-years) was 3.6% [95% CI: 3.5-3.7%] (range: 1.9% in UAE to 6.1% in Syria). COPD was more frequent (p < 0.0001) in men (5.2%) than in women (1.8%). The frequency of symptoms was significantly higher in cigarette smokers (p < 0.001), as well as in waterpipe users (p < 0.026). In conclusion, the prevalence of COPD in this region seems to be lower than that reported in industrialised countries. Under-reporting and risk factors other than smoking may contribute to this difference.
URI: https://doi.org/10.1016/S0954-6111(12)70012-4
https://www.sciencedirect.com/science/article/pii/S0954611112700124
http://hdl.handle.net/11452/24722
ISSN: 0954-6111
Appears in Collections:Scopus
Web of Science

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