Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/24823
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dc.date.accessioned2022-03-04T07:03:57Z-
dc.date.available2022-03-04T07:03:57Z-
dc.date.issued2005-03-
dc.identifier.citationTopal, A. vd. (2005). "Ondansetron and granisetron in the prophylaxis of nausea and emesis induced by cisplatin in dogs". Acta Veterinaria Brno, 74(1), 111-116.en_US
dc.identifier.issn0001-7213-
dc.identifier.urihttps://doi.org/10.2754/avb200574010111-
dc.identifier.urihttps://actavet.vfu.cz/74/1/0111/-
dc.identifier.urihttp://hdl.handle.net/11452/24823-
dc.description.abstractIn the present study, the effects of 5-HT3 receptor antagonist granisetron and ondansetron on the acute phase of cisplatin-induced nausea and emesis were analyzed in dogs. Fifteen healty dogs were used in this study. Cisplatin was administrated to all dogs to induce nausea and vomiting. All dogs that received cisplatin (3 mg/kg IV) were observed continuously for 8 It. Five dogs administered only cisplatin acted as controls. Cisplatin induced emetic response and nausea was detected in the controls. Ondansetron (1 mg/kg IV) and granisetron (60 mu g/kg IV) were administered to the other animals 30 min. before cisplatin administration. Although acute vomiting was significantly inhibited by ondansetron and granisetron, granisetron was found more effective on the nausea. It was concluded that both ondansetron and granisetron are effective in the control of cisplatin-induced vomiting in dogs, but granisetron is more effective than ondansetron in the inhibition of cisplatin-induced nausea in dogs.en_US
dc.language.isoenen_US
dc.publisherVeterinarni a Farmaceuticka Univerzita Brnoen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectVeterinary sciencesen_US
dc.subject5-HT3 receptor antagonisten_US
dc.subjectVomitingen_US
dc.subjectEmetic responseen_US
dc.subjectCanineen_US
dc.subjectDelayed emesisen_US
dc.subjectIn-vivoen_US
dc.subjectChemotherapyen_US
dc.subjectDexamethasoneen_US
dc.subjectZacoprideen_US
dc.subjectFerreten_US
dc.subjectPigeonen_US
dc.subjectModelen_US
dc.titleOndansetron and granisetron in the prophylaxis of nausea and emesis induced by cisplatin in dogsen_US
dc.typeArticleen_US
dc.identifier.wos000228165100016tr_TR
dc.identifier.scopus2-s2.0-17844364181tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Cerrahi Anabilim Dalı.tr_TR
dc.identifier.startpage111tr_TR
dc.identifier.endpage116tr_TR
dc.identifier.volume74tr_TR
dc.identifier.issue1tr_TR
dc.relation.journalActa Veterinaria Brnoen_US
dc.contributor.buuauthorTopal, Ayşe-
dc.contributor.buuauthorKaya, Metin-
dc.contributor.buuauthorGül, Nihal-
dc.subject.wosVeterinary sciencesen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid56357211200tr_TR
dc.contributor.scopusid55417963000tr_TR
dc.contributor.scopusid55899103700tr_TR
dc.subject.scopusPalonosetron; Fosaprepitant; Antiemeticsen_US
dc.subject.emtreeCisplatinen_US
dc.subject.emtreeGranisetronen_US
dc.subject.emtreeOndansetronen_US
dc.subject.emtreeAnimal cellen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeAnimal modelen_US
dc.subject.emtreeAnimal tissueen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug effecten_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMedical literatureen_US
dc.subject.emtreeNauseaen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreeVomitingen_US
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