Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/24921
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dc.date.accessioned2022-03-08T12:35:48Z-
dc.date.available2022-03-08T12:35:48Z-
dc.date.issued2005-
dc.identifier.citationKurt, M. vd. (2005). "Postoperative concomitant chemoradiotherapy in locally advanced rectal cancer". Hepato-Gastroenterology, 52(65), 1411-1415.en_US
dc.identifier.issn0172-6390-
dc.identifier.urihttp://hdl.handle.net/11452/24921-
dc.description.abstractBackground/Aims: To gain maximal effectiveness while decreasing toxicity by giving 5-fluorouracil for 45 minutes starting just within 5 minutes after the completion of radiotherapy thrice weekly. Methodology: Thirty-eight patients with locally advanced rectal cancer were enrolled in the study. Ranges of total radiation doses were between 50.4 Gy and 61.2 Gy with a median of 59.4 Gy with fraction size of 1.8 Gy five times weekly. 5-fluorouracil was administered thrice weekly with the dose of 250300mg/m(2)/day concomitantly with radiation therapy. Results: Median follow-up time was 30 months. Administration of chemotherapy concomitant with radiotherapy (p=0.089), AJCC stage III (p=0.079), Duke's stage C (p=0.079), presence of lymph node involvement (p=0.079) and presence of local recurrence (p=0.066) appeared to be effecting distant metastasis although differences did not reach statistically significance. Mean overall survival was 46 months in patients without any distant metastasis (SD: 3.28; 95% CI: 39.46 and 52.31) while it was 35 months in patients with distant metastasis (SD: 5.71; 95% CI: 23.52 and 45.90, p = 0.0 16). Conclusions: Our results have provided further evidence of the ability of postoperative chemoradiotherapy to delay and prevent local recurrence and metastasis of rectal cancer.en_US
dc.language.isoenen_US
dc.publisherH G E Update Medical Publishingen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGastroenterology & hepatologyen_US
dc.subjectSurgeryen_US
dc.subjectPostoperativeen_US
dc.subjectChemoradiotherapyen_US
dc.subjectRectal canceren_US
dc.subjectPreoperative infusional chemoradiationen_US
dc.subjectRadiation-therapyen_US
dc.subjectColorectal-canceren_US
dc.subjectAdjuvant therapyen_US
dc.subjectDistal rectumen_US
dc.subjectAdenocarcinomaen_US
dc.subjectRadiotherapyen_US
dc.subjectCarcinomaen_US
dc.subjectResectionen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAntimetabolites, antineoplasticen_US
dc.subject.meshFemaleen_US
dc.subject.meshFluorouracilen_US
dc.subject.meshHumansen_US
dc.subject.meshLife tablesen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNeoplasm stagingen_US
dc.subject.meshPostoperative perioden_US
dc.subject.meshRadiotherapy dosageen_US
dc.subject.meshRectal neoplasmsen_US
dc.titlePostoperative concomitant chemoradiotherapy in locally advanced rectal canceren_US
dc.typeArticleen_US
dc.identifier.wos000232127700022tr_TR
dc.identifier.scopus2-s2.0-25844478052tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyasyon Onkolojisi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Cerrahi Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Gastroenteroloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-1637-910Xtr_TR
dc.contributor.orcid0000-0002-2382-290Xtr_TR
dc.identifier.startpage1411tr_TR
dc.identifier.endpage1415tr_TR
dc.identifier.volume52tr_TR
dc.identifier.issue65tr_TR
dc.relation.journalHepato-Gastroenterologyen_US
dc.contributor.buuauthorKurt, Meral-
dc.contributor.buuauthorÖzkan, Lütfi-
dc.contributor.buuauthorYılmazlar, Tuncay-
dc.contributor.buuauthorErcan, İlker-
dc.contributor.buuauthorZorluoǧlu, Abdullah-
dc.contributor.buuauthorMemik, Faruk-
dc.contributor.buuauthorEngin, Kayıhan-
dc.contributor.researcheridAAA-3961-2020tr_TR
dc.identifier.pubmed16201085tr_TR
dc.subject.wosGastroenterology & hepatologyen_US
dc.subject.wosSurgeryen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ4 (Gastroenterology & hepatology)en_US
dc.wos.quartileQ3 (Surgery)en_US
dc.contributor.scopusid8843050600tr_TR
dc.contributor.scopusid55915679400tr_TR
dc.contributor.scopusid6701800362tr_TR
dc.contributor.scopusid6603789069tr_TR
dc.contributor.scopusid6602076843tr_TR
dc.contributor.scopusid6701813462tr_TR
dc.contributor.scopusid6701768798tr_TR
dc.subject.scopusRectum Tumor; Chemoradiotherapy; Organ Preservationen_US
dc.subject.emtreeFluorouracilen_US
dc.subject.emtreeFolinic aciden_US
dc.subject.emtreeLevamisoleen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAdvanced canceren_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeCancer recurrenceen_US
dc.subject.emtreeCancer stagingen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeGastrointestinal symptomen_US
dc.subject.emtreeHematologic diseaseen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMetastasisen_US
dc.subject.emtreePostoperative careen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeRadiation doseen_US
dc.subject.emtreeRectum canceren_US
dc.subject.emtreeSkin manifestationen_US
dc.subject.emtreeSurvival rateen_US
dc.subject.emtreeUrogenital tract diseaseen_US
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