1. Açık Erişim@BUU
  2. İndeksli Yayınlar
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Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/25062
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dc.contributor.authorBeksaç, Meral-
dc.contributor.authorÖzcan, Muhit-
dc.contributor.authorÖzçebe, Osman-
dc.contributor.authorBayık, Mahmut-
dc.contributor.authorPaydaş, Semra-
dc.contributor.authorBüyükaşık, Yahya-
dc.contributor.authorİlhan, Osman-
dc.contributor.authorGürman, Günhan-
dc.contributor.authorUysal, Akın-
dc.contributor.authorAkan, Hamdi-
dc.contributor.authorSoydan, Ender Akcağlayan-
dc.date.accessioned2022-03-16T06:25:28Z-
dc.date.available2022-03-16T06:25:28Z-
dc.date.issued2011-03-
dc.identifier.citationBeksaç, M. vd. (2011). "Short and long term effects of granulocyte colony-stimulating factor during induction therapy in acute myeloid leukemia patients younger than 65: Results of a randomized multicenter phase III trial". Leukemia Research, 35(3), 340-345.en_US
dc.identifier.issn0145-2126-
dc.identifier.issn1873-5835-
dc.identifier.urihttps://doi.org/10.1016/j.leukres.2010.07.005-
dc.identifier.urihttp://hdl.handle.net/11452/25062-
dc.description.abstractThis prospective multicenter phase III clinical trial was designed to assess efficacy and safety of G-CSF as an adjunct to de novo AML remission induction therapy (www.clinicaltrials.gov.NCT00820976). Patients' characteristics were similar in both arms. G-CSF improved severity and duration of leukopenia. Three-year OS were similar (25.6 +/- 5.1% vs. 31.8 +/- 5.6%) in both arms except for patients with myeloblastic features. Significant factors for better survival were the use of G-CSF (p = 0.049), female sex (p = 0.05) and single induction cycle (p < 0.001) in multivariate analysis. Female patients performed better than male patients. Better survival obtained among female AML patients needs to be validated within the context of cytogenetic analysis.en_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Scienceen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOncologyen_US
dc.subjectHematologyen_US
dc.subjectGranulocyte colony-stimulating factoren_US
dc.subjectAcute myeloid leukemiaen_US
dc.subjectInductionen_US
dc.subjectSurvivalen_US
dc.subjectAcute myelogenous leukemiaen_US
dc.subjectPlacebo-controlled trialen_US
dc.subjectSouthwest-oncology-groupen_US
dc.subjectElderly-patientsen_US
dc.subjectDouble-blinden_US
dc.subjectAdult patientsen_US
dc.subjectGrowth-factorsen_US
dc.subjectG-csfen_US
dc.subjectFebrile neutropeniaen_US
dc.subjectPrognostic-factorsen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshDrug resistance, neoplasmen_US
dc.subject.meshFemaleen_US
dc.subject.meshGranulocyte colony-stimulating factoren_US
dc.subject.meshHumansen_US
dc.subject.meshLeukemia, myeloid, acuteen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshNeoplasm recurrence, localen_US
dc.subject.meshNeutropeniaen_US
dc.subject.meshRemission inductionen_US
dc.subject.meshSurvival rateen_US
dc.subject.meshTime factorsen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshYoung adulten_US
dc.titleShort and long term effects of granulocyte colony-stimulating factor during induction therapy in acute myeloid leukemia patients younger than 65: Results of a randomized multicenter phase III trialen_US
dc.typeArticleen_US
dc.identifier.wos000287965100019tr_TR
dc.identifier.scopus2-s2.0-79952105259tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Hematoloji Anabilim Dalı.tr_TR
dc.identifier.startpage340tr_TR
dc.identifier.endpage345tr_TR
dc.identifier.volume35tr_TR
dc.identifier.issue3tr_TR
dc.relation.journalLeukemia Researchen_US
dc.contributor.buuauthorAli, Ridvan-
dc.contributor.buuauthorÖzçelik, Tülay-
dc.contributor.buuauthorÖzkalemkaş, Fahir-
dc.contributor.buuauthorTunalı, Ahmet-
dc.contributor.researcheridAAG-8495-2021tr_TR
dc.relation.collaborationYurt içitr_TR
dc.identifier.pubmed20673585tr_TR
dc.subject.wosOncologyen_US
dc.subject.wosHematologyen_US
dc.indexed.wosSSCIen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubmeden_US
dc.wos.quartileQ4en_US
dc.contributor.scopusid7201813027tr_TR
dc.contributor.scopusid7005424333tr_TR
dc.contributor.scopusid6601912387tr_TR
dc.subject.scopusCytarabine; Acute Myeloid Leukemia; Remissionen_US
dc.subject.emtreeCytarabineen_US
dc.subject.emtreeIdarubicinen_US
dc.subject.emtreeRecombinant granulocyte colony stimulating factoren_US
dc.subject.emtreeAcute febrile neutrophilic dermatosisen_US
dc.subject.emtreeAcute granulocytic leukemiaen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAllogeneic peripheral blood stem cell transplantationen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeAutologous peripheral blood stem cell transplantationen_US
dc.subject.emtreeBone marrow biopsyen_US
dc.subject.emtreeCapillary leak syndromeen_US
dc.subject.emtreeChromosome analysisen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDisease durationen_US
dc.subject.emtreeDisease severityen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeDrug eruptionen_US
dc.subject.emtreeDrug feveren_US
dc.subject.emtreeDrug safetyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHuman tissueen_US
dc.subject.emtreeInfectionen_US
dc.subject.emtreeLeukemia remissionen_US
dc.subject.emtreeLeukopeniaen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMulticenter studyen_US
dc.subject.emtreeMultiple cycle treatmenten_US
dc.subject.emtreeMusculoskeletal painen_US
dc.subject.emtreeMyoblasten_US
dc.subject.emtreeNeutrophil counten_US
dc.subject.emtreeOverall survivalen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProspective studyen_US
dc.subject.emtreeRandomized controlled trialen_US
dc.subject.emtreeSex differenceen_US
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