Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/25277
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dc.contributor.authorKarasu, Zeki-
dc.contributor.authorUlukaya, Sezgin-
dc.contributor.authorAyanoǧlu, Hilmi Ömer-
dc.contributor.authorAkyıldız, Murat-
dc.contributor.authorTokat, Yaman-
dc.date.accessioned2022-03-22T12:57:00Z-
dc.date.available2022-03-22T12:57:00Z-
dc.date.issued2004-11-
dc.identifier.citationKarasu, Z. vd. (2004). “Cytokine gene polymorphism and early graft rejection in liver transplant recipients”. Transplantation Proceedings, 36(9), 2791-2795.en_US
dc.identifier.issn0041-1345-
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2004.10.034-
dc.identifier.urihttp://hdl.handle.net/11452/25277-
dc.description.abstractCytokines, which play important roles in allograft rejection, show variable production among individuals. These variations may be related to genetic polymorphisms within the regulatory regions of the cytokine genes. We investigated the association between the role tumor necrosis factor alpha (TNF-α), transforming growth factor-beta (TGF-β), interferon gamma (IFN-γ), interleukin (IL)-10 and IL-6 gene polymorphisms and early graft rejection among liver transplant recipients. Forty-three liver transplant recipients enrolled in this study were divided into 2 groups based on events in the first 2 months posttransplantations, namely, those experiencing at least 1 rejection episode (n = 26) or those without any episode (n = 17). The allele or genotype frequencies of cytokine gene polymorphisms showed no difference between liver recipients with or without nonrejection. In conclusion, there was no significant correlation between early graft rejection and cytokine gene polymorphism of TNF-α, TGF-β, IL-10, IL-6, and IFN-γ in liver transplant recipients.en_US
dc.language.isoenen_US
dc.publisherElsevier Scienceen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectImmunologyen_US
dc.subjectSurgeryen_US
dc.subjectTransplantationen_US
dc.subjectNecrosis-factor-alphaen_US
dc.subjectRenal-allograft rejectionen_US
dc.subjectPromoter polymorphismsen_US
dc.subjectHeart-transplantationen_US
dc.subjectInterleukin-10 geneen_US
dc.subjectInterferon-gammaen_US
dc.subjectTNF-alphaen_US
dc.subjectKidneyen_US
dc.subjectAssociationen_US
dc.subjectGenotypesen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshBase sequenceen_US
dc.subject.meshCytokinesen_US
dc.subject.meshFemaleen_US
dc.subject.meshGene expression regulationen_US
dc.subject.meshGenotypeen_US
dc.subject.meshGraft rejectionen_US
dc.subject.meshHumansen_US
dc.subject.meshLiver transplantationen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPhenotypeen_US
dc.subject.meshPolymorphism, geneticen_US
dc.titleCytokine gene polymorphism and early graft rejection in liver transplant recipientsen_US
dc.typeArticleen_US
dc.identifier.wos000226142100072tr_TR
dc.identifier.scopus2-s2.0-11144251689tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İmmunoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Biyokimya Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-8784-1974tr_TR
dc.identifier.startpage2791tr_TR
dc.identifier.endpage2795tr_TR
dc.identifier.volume36tr_TR
dc.identifier.issue9tr_TR
dc.relation.journalTransplantation Proceedingsen_US
dc.contributor.buuauthorBaştürk, Bilkay-
dc.contributor.buuauthorUlukaya, Engin-
dc.contributor.researcheridAAD-6918-2021tr_TR
dc.contributor.researcheridK-5792-2018tr_TR
dc.relation.collaborationYurt içitr_TR
dc.identifier.pubmed15621151tr_TR
dc.subject.wosImmunologyen_US
dc.subject.wosSurgeryen_US
dc.subject.wosTransplantationen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.contributor.scopusid55910304400tr_TR
dc.contributor.scopusid6602927353tr_TR
dc.subject.scopusKidney Transplantation; Genetic Polymorphism; Graft Rejectionen_US
dc.subject.emtreeCyclosporinen_US
dc.subject.emtreeCytokineen_US
dc.subject.emtreeGamma interferonen_US
dc.subject.emtreeInterleukin 10en_US
dc.subject.emtreeInterleukin 6en_US
dc.subject.emtreeMethylprednisoloneen_US
dc.subject.emtreeSteroiden_US
dc.subject.emtreeTacrolimusen_US
dc.subject.emtreeTransforming growth factor betaen_US
dc.subject.emtreeTumor necrosis factor alphaen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCorrelation analysisen_US
dc.subject.emtreeDNA extractionen_US
dc.subject.emtreeDNA polymorphismen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGene frequencyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLiver graften_US
dc.subject.emtreeLiver graft rejectionen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreePolymerase chain reactionen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProtein functionen_US
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