Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/25510
Title: Diagnostic value of serum high mobility group box protein 1 (HMGB1) and soluble CD163 (sCD163) levels in brucellosis
Authors: Uludağ Üniversitesi/Tıp Fakültesi.
0000-0003-0463-6818
Ayarcı, Ayşe Oǧuz
Yılmaz, Emel
Sığırlı, Deniz
Budak, Ferah
Göral, Güher
Oral, Haluk Barbaros
F-4657-2014
AAA-7472-2021
K-7285-2012
Keywords: Immunology
Issue Date: Sep-2012
Publisher: Wiley
Citation: Ayarcı, A. O. vd. (2012). "Diagnostic value of serum high mobility group box protein 1 (HMGB1) and soluble CD163 (sCD163) levels in brucellosis". Immunology, 137(Supplement 1), Special Issue, 669-670.
Abstract: Both CD4+ and CD8+ T lymphocytes play critical roles in immunity to Brucella, in part because they secrete IFN-c and activate the bactericidal functions in macrophages. Therefore, use of markers which can evaluate macrophage activation may have diagnostic and prognostic importance. High mobility group-box 1 protein (HMGB1) is a late-onset proinflammatory cytokine secreted from activated macrophages. Soluble hemoglobin scavenger receptor (sCD163) is a specific marker of antiinflammatory macrophages. The aim of this study was to test potential associations of serum levels of HMGB1 and sCD163 with Brucellosis and its acute, subacute and chronic forms
Description: Bu çalışma, 05-08Eylül 2012 tarihleri arasında Glasgow[İskoçya]’da düzenlenen European Congress of Immunology’da bildiri olarak sunulmuştur.
URI: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458242/pdf/imm0137-0185.pdf
http://hdl.handle.net/11452/25510
ISSN: 0019-2805
Appears in Collections:Web of Science

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