Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/25700
Title: The variant translocation of ABL1 Gene t(2;9)(q21;q34) in a childhood T-cell acute lymphoblastic leukemia
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Hematoloji Anabilim Dalı.
Karkucak, Mutlu
Yakut, Tahsin
Baytan, Birol
Gülten, Tuna
Güneş, Adalet Meral
35388323500
6602802424
6506622162
6505944216
55543317800
Keywords: General & internal medicine
Abl1 gene translocation
T cell all
Prognostic-significance
Fusion
Issue Date: 2012
Publisher: Comenius University
Citation: Karkucak, M. vd. (2012). "The variant translocation of ABL1 Gene t(2;9)(q21;q34) in a childhood T-cell acute lymphoblastic leukemia". Bratislava Medical Journal, 113(1), 19-20.
Abstract: We present the case of the childhood ALL that was identified by the translocation of the ABL1 gene to the q21 band of chromosome 2 without t(9;22)(q34;q11) translocation. The observation of a poor clinical course of the case may contribute to explanation of the action of t(9;22)(q34;q11) translocation, of which poor prognostic action is known on ALL's, in terms of ABL1 gene, independent of the BCR gene. On the other hand, the prognostic significance of this variant ABL1 translocation detection, which is very rarely observed, will cast a light on future cases (Tab. 1, Fig. 1, Ref. 11). Full Text in free PDF www.bmj.sk.
URI: https://doi.org/10.4149/BLL_2012_004
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http://hdl.handle.net/11452/25700
ISSN: 0006-9248
Appears in Collections:Scopus
Web of Science

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