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Title: | The variant translocation of ABL1 Gene t(2;9)(q21;q34) in a childhood T-cell acute lymphoblastic leukemia |
Authors: | Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Genetik Anabilim Dalı. Uludağ Üniversitesi/Tıp Fakültesi/Pediatrik Hematoloji Anabilim Dalı. Karkucak, Mutlu Yakut, Tahsin Baytan, Birol Gülten, Tuna Güneş, Adalet Meral 35388323500 6602802424 6506622162 6505944216 55543317800 |
Keywords: | General & internal medicine Abl1 gene translocation T cell all Prognostic-significance Fusion |
Issue Date: | 2012 |
Publisher: | Comenius University |
Citation: | Karkucak, M. vd. (2012). "The variant translocation of ABL1 Gene t(2;9)(q21;q34) in a childhood T-cell acute lymphoblastic leukemia". Bratislava Medical Journal, 113(1), 19-20. |
Abstract: | We present the case of the childhood ALL that was identified by the translocation of the ABL1 gene to the q21 band of chromosome 2 without t(9;22)(q34;q11) translocation. The observation of a poor clinical course of the case may contribute to explanation of the action of t(9;22)(q34;q11) translocation, of which poor prognostic action is known on ALL's, in terms of ABL1 gene, independent of the BCR gene. On the other hand, the prognostic significance of this variant ABL1 translocation detection, which is very rarely observed, will cast a light on future cases (Tab. 1, Fig. 1, Ref. 11). Full Text in free PDF www.bmj.sk. |
URI: | https://doi.org/10.4149/BLL_2012_004 http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=2622&category_id=85&option=com_virtuemart&vmcchk=1&Itemid=1 http://hdl.handle.net/11452/25700 |
ISSN: | 0006-9248 |
Appears in Collections: | Scopus Web of Science |
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Karkucak_vd_2012.pdf | 1.28 MB | Adobe PDF | View/Open |
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