Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/28654
Title: Fatal breakthrough infection with Fusarium andiyazi: New multi-resistant aetiological agent cross-reacting with Aspergillus galactomannan enzyme immunoassay
Authors: van Diepeningen, Anne D.
Meijer, Martin
Al-Hatmi, Abdullah M.S.
Uludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Mikrobiyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.
0000-0002-4803-8206
Kebabçı, Nesrin
Ener, Beyza
Ersal, Tuba
Özkocaman, Vildan
Ursavaş, Ahmet
Çetinoğlu, Ezgi Demirdöğen
Akalın, Halis
AAJ-4354-2021
AAI-3169-2021
AAH-1854-2021
AAG-8523-2021
AAU-8952-2020
56060994000
15053025300
56061031700
6603145040
8329319900
57189524206
57207553671
Keywords: Acute leukaemia
Posaconazole prophylaxis
Fusarium andiyazi
Fusarium fujikuroi species complex
Galactomannan
Breakthrough infections
DNA-sequence database
Posaconazole prophylaxis
European organization
Leukemia
Diagnosis
Disease
Patient
Assay
Rice
Dermatology
Mycology
Issue Date: Apr-2014
Publisher: Wiley
Citation: Kebabçı, N. vd. (2014). "Fatal breakthrough infection with Fusarium andiyazi: New multi-resistant aetiological agent cross-reacting with Aspergillus galactomannan enzyme immunoassay". Mycoses, 57(4), 249-255.
Abstract: Disseminated infections caused by members of the Fusarium fujikuroi species complex (FFSC) occur regularly in immunocompromised patients. Here, we present the first human case caused by FFSC-member Fusarium andiyazi. Fever, respiratory symptoms and abnormal computerised tomography findings developed in a 65-year-old man with acute myelogenous leukaemia who was under posaconazole prophylaxis during his remission-induction chemotherapy. During the course of infection, two consecutive blood galactomannan values were found to be positive, and two blood cultures yielded strains resembling Fusarium species, according to morphological appearance. The aetiological agent proved to be F. andiyazi based on multilocus sequence typing. The sequencing of the internal transcribed spacer region did not resolve the closely related members of the FFSC, but additional data on partial sequence of transcription elongation factor 1 alpha subunit did. A detailed morphological study confirmed the identification of F. andiyazi, which had previously only been reported as a plant pathogen affecting various food crops.
URI: https://doi.org/10.1111/myc.12142
https://onlinelibrary.wiley.com/doi/full/10.1111/myc.12142
http://hdl.handle.net/11452/28654
ISSN: 0933-7407
1439-0507
Appears in Collections:Scopus
Web of Science

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.