1. Açık Erişim@BUU
  2. İndeksli Yayınlar
  3. Web of Science
Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29346
Full metadata record
DC FieldValueLanguage
dc.contributor.authorSolak, Yalçın-
dc.contributor.authorSiriopol, Dimitrie-
dc.contributor.authorYılmaz, Mahmut İlker-
dc.contributor.authorOrtiz, Alberto-
dc.contributor.authorCovic, Adrian-
dc.contributor.authorKanbay, Mehmet-
dc.date.accessioned2022-11-03T10:39:21Z-
dc.date.available2022-11-03T10:39:21Z-
dc.date.issued2016-11-18-
dc.identifier.citationSolak, Y. vd. (2017). ''Colchicine in renal Medicine: New virtues of an ancient friend''. Blood Purification, 43(1-3), 125-135.en_US
dc.identifier.issn0253-5068-
dc.identifier.issn1421-9735-
dc.identifier.urihttps://doi.org/10.1159/000454669-
dc.identifier.urihttps://www.karger.com/Article/FullText/454669-
dc.identifier.urihttp://hdl.handle.net/11452/29346-
dc.description.abstractColchicine is a plant-derived alkaloid that disrupts the cell microtubule system and accumulates in neutrophils, inhibiting neutrophil adhesion and recruitment. Colchicine has been used extensively in the prevention and treatment of gouty arthritis attacks, familial Mediterranean fever attacks and resultant AA amyloidosis, and recurrent pericarditis. Colchicine also disrupts the intracellular traffic of additional inflammatory and fibrosis mediators. Renal fibrosis is the final common pathway of chronic renal disease. Colchicine had anti-fibrotic effects in experimental diabetic nephropathy, renal mass reduction, and cyclosporine nephrotoxicity among others and is undergoing clinical trials for non-diabetic metabolic syndrome and diabetic nephropathy. In this review, we summarize the anti-inflammatory and anti-fibrotic properties of colchicine in experimental and clinical studies in renal diseases or other fibrotic disease processes with renal consequences. We also discuss the potential future uses of colchicine in renal medicine and challenges faced with its use in patients with impaired kidney function.en_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectHematologyen_US
dc.subjectUrology & nephrologyen_US
dc.subjectColchicineen_US
dc.subjectFibrosisen_US
dc.subjectInflammationen_US
dc.subjectKidney diseaseen_US
dc.subjectFamilial mediterranean feveren_US
dc.subjectChronic cyclosporine nephrotoxicityen_US
dc.subjectInflammatory cell infiltrationen_US
dc.subjectPrimary systemic amyloidosisen_US
dc.subjectPrimary biliary-cirrhosisen_US
dc.subjectChronic kidney-diseaseen_US
dc.subjectDiabetic-nephropathyen_US
dc.subjectMolecular-mechanismsen_US
dc.subjectIinduced neuromyopathyen_US
dc.subjectInterstitial fibrosisen_US
dc.subject.meshAnti-iInflammatory agentsen_US
dc.subject.meshColchicineen_US
dc.subject.meshFibrosisen_US
dc.subject.meshHumansen_US
dc.subject.meshKidney diseasesen_US
dc.titleColchicine in renal Medicine: New virtues of an ancient frienden_US
dc.typeReviewen_US
dc.identifier.wos000395948100017tr_TR
dc.identifier.scopus2-s2.0-85006314284tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/İç Hastalıkları Anabilim Dalı/Nefroloji Anabilim Dalı.tr_TR
dc.identifier.startpage125tr_TR
dc.identifier.endpage135tr_TR
dc.identifier.volume43tr_TR
dc.identifier.issue1-3tr_TR
dc.relation.journalBlood Purificationen_US
dc.contributor.buuauthorYıldız, Abdulmecit-
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationYurt dışıtr_TR
dc.relation.collaborationSanayitr_TR
dc.identifier.pubmed27951538tr_TR
dc.subject.wosHematologyen_US
dc.subject.wosUrology & nephrologyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid56256977500tr_TR
dc.subject.scopusColchicine; Gloriosa Superba; Gouten_US
dc.subject.emtreeAlpha tubulinen_US
dc.subject.emtreeBeta tubulinen_US
dc.subject.emtreeC type lectin like receptoren_US
dc.subject.emtreeColchicin een_US
dc.subject.emtreeCollagen type 1en_US
dc.subject.emtreeCryopyrinen_US
dc.subject.emtreeCytochrome P450 3A4en_US
dc.subject.emtreeFibronectinen_US
dc.subject.emtreeInflammasomeen_US
dc.subject.emtreeInterleukin 18en_US
dc.subject.emtreeInterleukin 1betaen_US
dc.subject.emtreeLectinen_US
dc.subject.emtreeMmultidrug resistance protein 1en_US
dc.subject.emtreeSmad proteinen_US
dc.subject.emtreeTransforming growth factor beta1en_US
dc.subject.emtreeTumor necrosis factoren_US
dc.subject.emtreeUnclassified drugen_US
dc.subject.emtreeAntiinflammatory agenten_US
dc.subject.emtreeColchicineen_US
dc.subject.emtreeCell divisionen_US
dc.subject.emtreeChronic kidney failureen_US
dc.subject.emtreeDiabetic nephropathyen_US
dc.subject.emtreeDown regulationen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeDrug safetyen_US
dc.subject.emtreeExtracellular matrixen_US
dc.subject.emtreeHistopathologyen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeImmunomodulationen_US
dc.subject.emtreeKidney amyloidosisen_US
dc.subject.emtreeKidney diseaseen_US
dc.subject.emtreeKidney fibrosisen_US
dc.subject.emtreeKidney injuryen_US
dc.subject.emtreeKidney tumoren_US
dc.subject.emtreeLiver fibrosisen_US
dc.subject.emtreeNephrotoxicityen_US
dc.subject.emtreePeritoneal fibrosisen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeProtein phosphorylationen_US
dc.subject.emtreeReviewen_US
dc.subject.emtreeSystematic reviewen_US
dc.subject.emtreeFibrosisen_US
dc.subject.emtreeKidney diseasesen_US
dc.subject.emtreePathologyen_US
Appears in Collections:Web of Science

Files in This Item:
File Description SizeFormat 
Yıldız_vd_2017.pdf189.2 kBAdobe PDFThumbnail
View/Open
Show simple item record


This item is licensed under a Creative Commons License Creative Commons