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http://hdl.handle.net/11452/29512
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DC Field | Value | Language |
---|---|---|
dc.date.accessioned | 2022-11-21T08:38:22Z | - |
dc.date.available | 2022-11-21T08:38:22Z | - |
dc.date.issued | 2016-10 | - |
dc.identifier.citation | Sağ, S. vd. (2016). "Catheter-directed ultrasound-accelerated thrombolysis may be life-saving in patients with massive pulmonary embolism after failed systemic thrombolysis". Journal of Thrombosis and Thrombolysis, 42(3), 322-328. | en_US |
dc.identifier.issn | 0929-5305 | - |
dc.identifier.issn | 1573-742X | - |
dc.identifier.uri | https://doi.org/10.1007/s11239-016-1370-3 | - |
dc.identifier.uri | https://link.springer.com/article/10.1007/s11239-016-1370-3 | - |
dc.identifier.uri | http://hdl.handle.net/11452/29512 | - |
dc.description.abstract | The treatment options for high risk acute pulmonary embolism (PE) patients with failed systemic thrombolytic treatment (STT) is limited. The clinical use of catheter directed thrombolysis with the EkoSonic Endovascular System (EKOS) in this population has not been evaluated before. Catheter directed thrombolysis is an effective treatment modality for high risk PE patients with failed STT. Thirteen consecutive patients with failed STT were included in the study. EKOS catheters were placed and tissue plasminogen activator (t-PA) in combination with unfractionated heparin were given. Clinical and echocardiographic properties of the patients were collected before EKOS, at the end of EKOS and during the follow-up visit 6 months after discharge. The duration of EKOS treatment was 21.8 +/- 3.8 h and the total dose of tPA was 31.2 +/- 15.3 mg. One patient who presented with cardiac arrest died and the clinical status of the remaining subjects improved significantly. Any hemorrhagic complication was not observed. EKOS resulted in significant improvement of right ventricular functions and decrease of systolic pulmonary artery pressure. During a follow-up period of 6 months none of the patients died or suffered recurrent PE. In addition, echocardiographic parameters or right ventricular function significantly got better compared to in-hospital measurements. EKOS is an effective treatment modality for high risk PE patients with failed STT and can be applied with very low hemorrhagic complications. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Springer | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Cardiovascular system & cardiology | en_US |
dc.subject | Hematology | en_US |
dc.subject | Acute pulmonary embolism | en_US |
dc.subject | Failed systemic thrombolytic treatment | en_US |
dc.subject | Catheter directed thrombolysis | en_US |
dc.subject | EkoSonic endovascular system | en_US |
dc.subject | European-society | en_US |
dc.subject | Intermediate | en_US |
dc.subject | Embolectomy | en_US |
dc.subject | Therapy | en_US |
dc.subject | Fragmentation | en_US |
dc.subject | Fibrinolysis | en_US |
dc.subject | Guidelines | en_US |
dc.subject | Management | en_US |
dc.subject | Cardiology | en_US |
dc.subject | Safety | en_US |
dc.subject.mesh | Catheters | en_US |
dc.subject.mesh | Female | en_US |
dc.subject.mesh | Heparin | en_US |
dc.subject.mesh | Humans | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Mechanical thrombolysis | en_US |
dc.subject.mesh | Middle aged | en_US |
dc.subject.mesh | Pulmonary embolism | en_US |
dc.subject.mesh | Salvage therapy | en_US |
dc.subject.mesh | Thrombolytic therapy | en_US |
dc.subject.mesh | Tissue plasminogen activator | en_US |
dc.subject.mesh | Treatment outcome | en_US |
dc.subject.mesh | Ultrasonic surgical procedures | en_US |
dc.title | Catheter-directed ultrasound-accelerated thrombolysis may be life-saving in patients with massive pulmonary embolism after failed systemic thrombolysis | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000382868700002 | tr_TR |
dc.identifier.scopus | 2-s2.0-84964614216 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı. | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0001-8404-8252 | tr_TR |
dc.contributor.orcid | 0000-0002-3425-0740 | tr_TR |
dc.contributor.orcid | 0000-0002-8974-8837 | tr_TR |
dc.identifier.startpage | 322 | tr_TR |
dc.identifier.endpage | 328 | tr_TR |
dc.identifier.volume | 42 | tr_TR |
dc.identifier.issue | 3 | tr_TR |
dc.relation.journal | Journal of Thrombosis and Thrombolysis | en_US |
dc.contributor.buuauthor | Sağ, Saim | - |
dc.contributor.buuauthor | Nas, Ömer Fatih | - |
dc.contributor.buuauthor | Kaderli, Aysel Aydın | - |
dc.contributor.buuauthor | Özdemir, Bülent | - |
dc.contributor.buuauthor | Baran, İbrahim | - |
dc.contributor.buuauthor | Erdoğan, Cüneyt | - |
dc.contributor.buuauthor | Güllülü, Sümeyye | - |
dc.contributor.buuauthor | Hakyemez, Bahattin | - |
dc.contributor.buuauthor | Aydınlar, Ali | - |
dc.contributor.researcherid | AAW-9185-2020 | tr_TR |
dc.contributor.researcherid | AAG-8561-2021 | tr_TR |
dc.contributor.researcherid | AAI-2318-2021 | tr_TR |
dc.contributor.researcherid | AAI-6632-2021 | tr_TR |
dc.identifier.pubmed | 27129723 | tr_TR |
dc.subject.wos | Cardiac & cardiovascular systems | en_US |
dc.subject.wos | Hematology | en_US |
dc.subject.wos | Peripheral vascular disease | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q3 | en_US |
dc.contributor.scopusid | 12140008100 | tr_TR |
dc.contributor.scopusid | 51864050100 | tr_TR |
dc.contributor.scopusid | 7801322152 | tr_TR |
dc.contributor.scopusid | 7004168959 | tr_TR |
dc.contributor.scopusid | 35572557400 | tr_TR |
dc.contributor.scopusid | 8293835700 | tr_TR |
dc.contributor.scopusid | 57204660708 | tr_TR |
dc.contributor.scopusid | 6602527239 | tr_TR |
dc.contributor.scopusid | 6603131517 | tr_TR |
dc.subject.scopus | Lung Embolism; Embolectomy; Blood Clot Lysis | en_US |
dc.subject.emtree | Heparin | en_US |
dc.subject.emtree | Tissue plasminogen activator | en_US |
dc.subject.emtree | Absence of complications | en_US |
dc.subject.emtree | Acute pulmonary embolism | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Catheter directed thrombolysis | en_US |
dc.subject.emtree | Cause of death | en_US |
dc.subject.emtree | Clinical article | en_US |
dc.subject.emtree | Clinical assessment | en_US |
dc.subject.emtree | Controlled clinical trial | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Echocardiography | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Flush catheter | en_US |
dc.subject.emtree | Follow up | en_US |
dc.subject.emtree | Heart arrest | en_US |
dc.subject.emtree | Heart right ventricle function | en_US |
dc.subject.emtree | High risk patient | en_US |
dc.subject.emtree | Hospital discharge | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Lung artery pressure | en_US |
dc.subject.emtree | Lung embolism | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Mechanical thrombectomy | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Prospective study | en_US |
dc.subject.emtree | Systemic thrombolytic treatment | en_US |
dc.subject.emtree | Treatment duration | en_US |
dc.subject.emtree | Treatment failure | en_US |
dc.subject.emtree | Catheter | en_US |
dc.subject.emtree | Devices | en_US |
dc.subject.emtree | Evaluation study | en_US |
dc.subject.emtree | Fibrinolytic therapy | en_US |
dc.subject.emtree | Mechanical thrombectomy | en_US |
dc.subject.emtree | Middle aged | en_US |
dc.subject.emtree | Procedures | en_US |
dc.subject.emtree | Pulmonary embolism | en_US |
dc.subject.emtree | Salvage therapy | en_US |
dc.subject.emtree | Treatment outcome | en_US |
dc.subject.emtree | Ultrasound surgery | en_US |
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