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http://hdl.handle.net/11452/29618
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Escribano, Damian | - |
dc.contributor.author | Tvarijonaviciute, Asta | - |
dc.contributor.author | Joaquin Ceron, Jose | - |
dc.contributor.author | Pardo-Marin, Luis | - |
dc.contributor.author | Torrecillas, Alejandro | - |
dc.contributor.author | Martinez-Subiela, Silvia | - |
dc.date.accessioned | 2022-11-29T07:56:05Z | - |
dc.date.available | 2022-11-29T07:56:05Z | - |
dc.date.issued | 2016-10-10 | - |
dc.identifier.citation | Escribano, D. vd. (2016). "Serum apolipoprotein-A1 as a possible biomarker for monitoring treatment of canine leishmaniosis". Comparative Immunology Microbiology and Infectious Diseases, 49, 82-87. | en_US |
dc.identifier.issn | 0147-9571 | - |
dc.identifier.issn | 1878-1667 | - |
dc.identifier.uri | https://doi.org/10.1016/j.cimid.2016.10.002 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0147957116300984 | - |
dc.identifier.uri | http://hdl.handle.net/11452/29618 | - |
dc.description.abstract | The aims of this study were: the identification of proteins differentially represented in the serum proteome of dogs with leishmaniosis after treatment and the verification of one selected protein as a possible biomarker for treatment monitoring. Serum samples from five dogs with leishmaniosis, before and after treatment were pooled into two groups and analysed using 2-dimensional electrophoresis followed by mass spectrometry analysis (MS). The MS analysis allowed the identification of 8 proteins differently expressed. APO-A1 was selected and an immunoturbidimetric assay was validated for its measurement in dogs. Significantly decreased concentrations of APO-A1 in dogs with leishmaniosis and a significant increase after a good response to the treatment were observed, suggesting that APO-A1 could be a potential biomarker of treatment monitoring with the advantages of an automated measurement. | en_US |
dc.description.sponsorship | Robles Chillida foundation | en_US |
dc.description.sponsorship | Program for Research Groups of Excellence of the Seneca Foundation - 19894/GERM/15 | en_US |
dc.description.sponsorship | "Juan de la Cierva" postdoctoral fellowship (Spanish Ministry of Economy and Competitiveness) | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Immunology | en_US |
dc.subject | Microbiology | en_US |
dc.subject | Veterinary sciences | en_US |
dc.subject | Leishmaniosis | en_US |
dc.subject | Dogs | en_US |
dc.subject | Apolipoprotein A1 | en_US |
dc.subject | Treatment monitoring | en_US |
dc.subject | Visceral leishmaniasis | en_US |
dc.subject | Proteins | en_US |
dc.subject | Identification | en_US |
dc.subject | Proteomics | en_US |
dc.subject | Diagnosis | en_US |
dc.subject.mesh | Allopurinol | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Antiprotozoal agents | en_US |
dc.subject.mesh | Apolipoprotein A-I | en_US |
dc.subject.mesh | Biomarkers | en_US |
dc.subject.mesh | Dogs | en_US |
dc.subject.mesh | Electrophoresis, gel, two-dimensional | en_US |
dc.subject.mesh | Leishmaniasis | en_US |
dc.subject.mesh | Mass spectrometry | en_US |
dc.subject.mesh | Meglumine | en_US |
dc.subject.mesh | Organometallic compounds | en_US |
dc.subject.mesh | Proteome | en_US |
dc.title | Serum apolipoprotein-A1 as a possible biomarker for monitoring treatment of canine leishmaniosis | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000390521800011 | tr_TR |
dc.identifier.scopus | 2-s2.0-84993970544 | tr_TR |
dc.relation.tubitak | TOVAG-2130032 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Veteriner Fakültesi/Dahiliye Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0001-9836-0749 | tr_TR |
dc.identifier.startpage | 82 | tr_TR |
dc.identifier.endpage | 87 | tr_TR |
dc.identifier.volume | 49 | tr_TR |
dc.relation.journal | Comparative Immunology, Microbiology and Infectious Diseases | en_US |
dc.contributor.buuauthor | Kocatürk, Meriç | - |
dc.contributor.buuauthor | Yılmaz, Zeki | - |
dc.contributor.researcherid | V-5578-2017 | tr_TR |
dc.relation.collaboration | Yurt dışı | tr_TR |
dc.identifier.pubmed | 27865270 | tr_TR |
dc.subject.wos | Immunology | en_US |
dc.subject.wos | Microbiology | en_US |
dc.subject.wos | Veterinary sciences | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q4 (Immunology) | en_US |
dc.wos.quartile | Q3 (Microbiology) | en_US |
dc.wos.quartile | Q1 (Veterinary sciences) | en_US |
dc.contributor.scopusid | 36437200800 | tr_TR |
dc.contributor.scopusid | 35944810500 | tr_TR |
dc.subject.scopus | Leishmania Infantum; Dog; Psychodidae | en_US |
dc.subject.emtree | Alpha 1 antitrypsin | en_US |
dc.subject.emtree | Apolipoprotein A1 | en_US |
dc.subject.emtree | Biological marker | en_US |
dc.subject.emtree | Haptoglobin | en_US |
dc.subject.emtree | Hemoglobin beta chain | en_US |
dc.subject.emtree | Immunoglobulin lambda chain | en_US |
dc.subject.emtree | Meglumine | en_US |
dc.subject.emtree | Retinol binding protein 4 | en_US |
dc.subject.emtree | Vitamin D binding protein | en_US |
dc.subject.emtree | Allopurinol | en_US |
dc.subject.emtree | Antiprotozoal agent | en_US |
dc.subject.emtree | Apolipoprotein A1 | en_US |
dc.subject.emtree | Meglumine antimoniate | en_US |
dc.subject.emtree | Organometallic compound | en_US |
dc.subject.emtree | Proteome | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Blood sampling | en_US |
dc.subject.emtree | Canine leishmaniasis | en_US |
dc.subject.emtree | Drug response | en_US |
dc.subject.emtree | Leishmaniasis | en_US |
dc.subject.emtree | Limit of detection | en_US |
dc.subject.emtree | Mass spectrometry | en_US |
dc.subject.emtree | Monitoring | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Protein blood level | en_US |
dc.subject.emtree | Protein expression | en_US |
dc.subject.emtree | Proteomics | en_US |
dc.subject.emtree | Two dimensional electrophoresis | en_US |
dc.subject.emtree | Validity | en_US |
dc.subject.emtree | Animal | en_US |
dc.subject.emtree | Blood | en_US |
dc.subject.emtree | Chemistry | en_US |
dc.subject.emtree | Dog | en_US |
dc.subject.emtree | Leishmaniasis | en_US |
dc.subject.emtree | Two dimensional gel electrophoresis | en_US |
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