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http://hdl.handle.net/11452/29632
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DC Field | Value | Language |
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dc.date.accessioned | 2022-11-29T12:23:59Z | - |
dc.date.available | 2022-11-29T12:23:59Z | - |
dc.date.issued | 2016-08 | - |
dc.identifier.citation | Kaplan, M. A. vd. (2016). "Biological subtypes and distant relapse pattern in breast cancer patients after curative surgery (study of Anatolian society of medical oncology)". Breast Care, 11(4), 248-252. | en_US |
dc.identifier.issn | 1661-3791 | - |
dc.identifier.issn | 1661-3805 | - |
dc.identifier.uri | https://doi.org/10.1159/000448186 | - |
dc.identifier.uri | https://www.karger.com/Article/FullText/448186 | - |
dc.identifier.uri | http://hdl.handle.net/11452/29632 | - |
dc.description | Çalışmada 24 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır. | tr_TR |
dc.description.abstract | Purpose: The aim of the study was to investigate the association between the molecular subtypes and patterns of relapse in breast cancer patients who had undergone curative surgery. Methods: We retrospectively evaluated 1,350 breast cancer patients with relapses after curative surgery between 1998 and 2012 from referral centers in Turkey. Patients were divided into 4 biological subtypes according to immunohistochennistry and grade: triple negative, HER2 overexpressing, luminal A and luminal B. Results: The percentages of patients with luminal A, lumina! B, HER2-overexpressing, and triple-negative breast cancer were 32.9% (n = 444), 34.9% (n = 471), 12.0% (n = 162), and 20.2% (n = 273), respectively. The distribution of metastases differed among the subgroups: bone (66.2% and 53.9% in lumina! A and B vs. 38.9% in HER2-overexpressing and 45.1% in triple negative, p < 0.001), liver (40.1% in HER2-overexpressing vs. 24.5% in lumina! A, 33.5% in luminal B, and 27.5% in triple negative, p < 0.001), lung (41.4% in triple negative and 35.2% in HER2-overexpressing vs. 30.2% and 30.6% in luminal A and B, p = 0.008) and brain (25.3% in HER2overexpressing and 23.1% in triple negative vs. 10.1% and 15.1% in lumina! A and B, p < 0.001). Conclusions: Organ -specific metastasis may depend on the molecular subtype of breast cancer. Tailored strategies against distant metastasis concerning the molecular subtypes in breast cancer should be considered. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Karger | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.rights | Atıf Gayri Ticari Türetilemez 4.0 Uluslararası | tr_TR |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | * |
dc.subject | Oncology | en_US |
dc.subject | Obstetrics & gynecology | en_US |
dc.subject | Breast cancer | en_US |
dc.subject | Relapse pattern | en_US |
dc.subject | Molecular subtype | en_US |
dc.subject | Molecular subtypes | en_US |
dc.subject | Prognostic-factors | en_US |
dc.subject | Metastasis | en_US |
dc.subject | Recurrence | en_US |
dc.subject | Survival | en_US |
dc.subject | Women | en_US |
dc.subject | Risk | en_US |
dc.subject | Estrogen | en_US |
dc.subject | Genes | en_US |
dc.subject | Site | en_US |
dc.title | Biological subtypes and distant relapse pattern in breast cancer patients after curative surgery (study of Anatolian society of medical oncology) | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000383220300003 | tr_TR |
dc.identifier.scopus | 2-s2.0-84981516957 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Onkoloji Anabilim Dalı. | tr_TR |
dc.identifier.startpage | 248 | tr_TR |
dc.identifier.endpage | 252 | tr_TR |
dc.identifier.volume | 11 | tr_TR |
dc.identifier.issue | 4 | tr_TR |
dc.relation.journal | Breast Care | en_US |
dc.contributor.buuauthor | Çubukçu, Erdem | - |
dc.relation.collaboration | Yurt içi | tr_TR |
dc.relation.collaboration | Sanayi | tr_TR |
dc.identifier.pubmed | 27721711 | tr_TR |
dc.subject.wos | Oncology | en_US |
dc.subject.wos | Obstetrics & gynecology | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q3 (Obstetrics & gynecology) | en_US |
dc.wos.quartile | Q4 (Oncology) | en_US |
dc.contributor.scopusid | 53986153800 | tr_TR |
dc.subject.scopus | Triple Negative Breast Neoplasms; Negative; Hormone Receptors | en_US |
dc.subject.emtree | Adult | en_US |
dc.subject.emtree | Aged | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Bone metastasis | en_US |
dc.subject.emtree | Brain metastasis | en_US |
dc.subject.emtree | Breast cancer | en_US |
dc.subject.emtree | Cancer recurrence | en_US |
dc.subject.emtree | Disease free survival | en_US |
dc.subject.emtree | Female | en_US |
dc.subject.emtree | Her2 overexpressing breast cancer | en_US |
dc.subject.emtree | Human | en_US |
dc.subject.emtree | Liver metastasis | en_US |
dc.subject.emtree | Luminal A breast cancer | en_US |
dc.subject.emtree | Luminal B breast cancer | en_US |
dc.subject.emtree | Lung metastasis | en_US |
dc.subject.emtree | Major clinical study | en_US |
dc.subject.emtree | Medical record review | en_US |
dc.subject.emtree | Metastasis | en_US |
dc.subject.emtree | Overall survival | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Triple negative breast cancer | en_US |
Appears in Collections: | Scopus Web of Science |
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