Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29632
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dc.date.accessioned2022-11-29T12:23:59Z-
dc.date.available2022-11-29T12:23:59Z-
dc.date.issued2016-08-
dc.identifier.citationKaplan, M. A. vd. (2016). "Biological subtypes and distant relapse pattern in breast cancer patients after curative surgery (study of Anatolian society of medical oncology)". Breast Care, 11(4), 248-252.en_US
dc.identifier.issn1661-3791-
dc.identifier.issn1661-3805-
dc.identifier.urihttps://doi.org/10.1159/000448186-
dc.identifier.urihttps://www.karger.com/Article/FullText/448186-
dc.identifier.urihttp://hdl.handle.net/11452/29632-
dc.descriptionÇalışmada 24 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.tr_TR
dc.description.abstractPurpose: The aim of the study was to investigate the association between the molecular subtypes and patterns of relapse in breast cancer patients who had undergone curative surgery. Methods: We retrospectively evaluated 1,350 breast cancer patients with relapses after curative surgery between 1998 and 2012 from referral centers in Turkey. Patients were divided into 4 biological subtypes according to immunohistochennistry and grade: triple negative, HER2 overexpressing, luminal A and luminal B. Results: The percentages of patients with luminal A, lumina! B, HER2-overexpressing, and triple-negative breast cancer were 32.9% (n = 444), 34.9% (n = 471), 12.0% (n = 162), and 20.2% (n = 273), respectively. The distribution of metastases differed among the subgroups: bone (66.2% and 53.9% in lumina! A and B vs. 38.9% in HER2-overexpressing and 45.1% in triple negative, p < 0.001), liver (40.1% in HER2-overexpressing vs. 24.5% in lumina! A, 33.5% in luminal B, and 27.5% in triple negative, p < 0.001), lung (41.4% in triple negative and 35.2% in HER2-overexpressing vs. 30.2% and 30.6% in luminal A and B, p = 0.008) and brain (25.3% in HER2overexpressing and 23.1% in triple negative vs. 10.1% and 15.1% in lumina! A and B, p < 0.001). Conclusions: Organ -specific metastasis may depend on the molecular subtype of breast cancer. Tailored strategies against distant metastasis concerning the molecular subtypes in breast cancer should be considered.en_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectOncologyen_US
dc.subjectObstetrics & gynecologyen_US
dc.subjectBreast canceren_US
dc.subjectRelapse patternen_US
dc.subjectMolecular subtypeen_US
dc.subjectMolecular subtypesen_US
dc.subjectPrognostic-factorsen_US
dc.subjectMetastasisen_US
dc.subjectRecurrenceen_US
dc.subjectSurvivalen_US
dc.subjectWomenen_US
dc.subjectRisken_US
dc.subjectEstrogenen_US
dc.subjectGenesen_US
dc.subjectSiteen_US
dc.titleBiological subtypes and distant relapse pattern in breast cancer patients after curative surgery (study of Anatolian society of medical oncology)en_US
dc.typeArticleen_US
dc.identifier.wos000383220300003tr_TR
dc.identifier.scopus2-s2.0-84981516957tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Onkoloji Anabilim Dalı.tr_TR
dc.identifier.startpage248tr_TR
dc.identifier.endpage252tr_TR
dc.identifier.volume11tr_TR
dc.identifier.issue4tr_TR
dc.relation.journalBreast Careen_US
dc.contributor.buuauthorÇubukçu, Erdem-
dc.relation.collaborationYurt içitr_TR
dc.relation.collaborationSanayitr_TR
dc.identifier.pubmed27721711tr_TR
dc.subject.wosOncologyen_US
dc.subject.wosObstetrics & gynecologyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ3 (Obstetrics & gynecology)en_US
dc.wos.quartileQ4 (Oncology)en_US
dc.contributor.scopusid53986153800tr_TR
dc.subject.scopusTriple Negative Breast Neoplasms; Negative; Hormone Receptorsen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBone metastasisen_US
dc.subject.emtreeBrain metastasisen_US
dc.subject.emtreeBreast canceren_US
dc.subject.emtreeCancer recurrenceen_US
dc.subject.emtreeDisease free survivalen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeHer2 overexpressing breast canceren_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLiver metastasisen_US
dc.subject.emtreeLuminal A breast canceren_US
dc.subject.emtreeLuminal B breast canceren_US
dc.subject.emtreeLung metastasisen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMedical record reviewen_US
dc.subject.emtreeMetastasisen_US
dc.subject.emtreeOverall survivalen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeTriple negative breast canceren_US
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