Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29754
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dc.date.accessioned2022-12-08T10:50:44Z-
dc.date.available2022-12-08T10:50:44Z-
dc.date.issued2015-01-
dc.identifier.citationOran, S. vd. (2016). "Antioxidant and antimicrobial potential, and HPLC analysis of stictic and usnic acids of three Usnea species from Uludag mountain (Bursa, Turkey)". Iranian Journal of Pharmaceutical Research, 15(2), 527-535.en_US
dc.identifier.issn1735-0328-
dc.identifier.issn1726-6890-
dc.identifier.urihttps://pubmed.ncbi.nlm.nih.gov/27642324/-
dc.identifier.urihttp://hdl.handle.net/11452/29754-
dc.description.abstractIn this study, antioxidant and antimicrobial potentials of Usnea intermedia, U. filipendula, and U. fulvoreagens and their stictic and usnic acid contents were investigated. Antioxidant activity and total phenolic contents were evaluated in acetone, ethanol, and methanol extracts of these three species. Antioxidant activity was measured by ABTS [2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulphonic acid)] method and total phenolic contents were measured by Folin-Ciocalteu method. High-performance liquid chromatography (HPLC) was used for the determination of lichen acids. It can be concluded from stictic and usnic acids contents that the order of solvent efficiency is acetone > ethanol > methanol and acetone > methanol > ethanol, respectively. Broth microdilution method was performed to determine the minimum inhibitory concentration (MIC) of the methanol extracts of three Usnea species. The MIC values of all the extracts ranged from 64 mu g/mL to 512 mu g/mL for all the bacterial strains that were tested in this study, and all the Fluoro quinolone-resistant Escherichia coli isolates (except for E101) were sensitive to the methanol extracts of the three Usnea species. This paper is the first study to determine the stictic acid content in U. intermedia and U. filipendula. Our findings indicate that these three Usnea species could be used as antioxidant and antimicrobial agents.en_US
dc.language.isoenen_US
dc.publisherShaheed Beheshtien_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPharmacology & pharmacyen_US
dc.subjectStictic aciden_US
dc.subjectUsnea fulvoreagensen_US
dc.subjectUsnea filipendulaen_US
dc.subjectUsnea intermediaen_US
dc.subjectUsnic aciden_US
dc.subjectSecondary metabolitesen_US
dc.subjectHypogymnia-physodesen_US
dc.subjectPhenolic contenten_US
dc.subjectLichensen_US
dc.subjectExtractsen_US
dc.subjectConstituentsen_US
dc.titleAntioxidant and antimicrobial potential, and HPLC analysis of stictic and usnic acids of three Usnea species from Uludag mountain (Bursa, Turkey)en_US
dc.typeArticleen_US
dc.identifier.wos000377527300016tr_TR
dc.identifier.scopus2-s2.0-84973640205tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü.tr_TR
dc.contributor.departmentBursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Veteriner Fakültesi/Farmakoloji ve Toksikoloji Anabilim Dalı/Moleküler Farmakoloji Laboratuvarı.tr_TR
dc.relation.bapUAP(F)-2011/43tr_TR
dc.contributor.orcid0000-0001-8196-2065tr_TR
dc.contributor.orcid0000-0003-1508-0181tr_TR
dc.contributor.orcid0000-0003-1508-0181tr_TR
dc.contributor.orcid0000-0002-9381-0410tr_TR
dc.identifier.startpage527tr_TR
dc.identifier.endpage535tr_TR
dc.identifier.volume15tr_TR
dc.identifier.issue2tr_TR
dc.relation.journalIranian Journal of Pharmaceutical Researchen_US
dc.contributor.buuauthorOran, Seyhan-
dc.contributor.buuauthorŞahin, Saliha-
dc.contributor.buuauthorŞahintürk, Pınar-
dc.contributor.buuauthorÖztürk, Şule-
dc.contributor.buuauthorDemir, Cevdet-
dc.contributor.researcheridAAH-5039-2021tr_TR
dc.contributor.researcheridAAH-2892-2021tr_TR
dc.contributor.researcheridAFR-1890-2022tr_TR
dc.contributor.researcheridAAD-7322-2019tr_TR
dc.contributor.researcheridABA-2005-2020tr_TR
dc.identifier.pubmed27642324tr_TR
dc.subject.wosPharmacology & pharmacyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ4en_US
dc.contributor.scopusid14067648200tr_TR
dc.contributor.scopusid15027401600tr_TR
dc.contributor.scopusid55342852700tr_TR
dc.contributor.scopusid7004555373tr_TR
dc.contributor.scopusid7003565902tr_TR
dc.subject.scopusUsnic Acid; Extract; Lichen (Disease)en_US
dc.subject.emtreeABTS radical scavenging assayen_US
dc.subject.emtreeAntibacterial activityen_US
dc.subject.emtreeAntioxidant activityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBacterial strainen_US
dc.subject.emtreeBroth dilutionen_US
dc.subject.emtreeDrug determinationen_US
dc.subject.emtreeEscherichia colien_US
dc.subject.emtreeFilipendulaen_US
dc.subject.emtreeHigh performance liquid chromatographyen_US
dc.subject.emtreeLimit of detectionen_US
dc.subject.emtreeLimit of quantitationen_US
dc.subject.emtreeMinimum inhibitory concentrationen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreeSolvent extractionen_US
dc.subject.emtreeStaphylococcus aureusen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeUsneaen_US
dc.subject.emtreeValidation processen_US
dc.subject.emtreeABTS radical scavenging assayen_US
dc.subject.emtreeAntibacterial activityen_US
dc.subject.emtreeAntioxidant activityen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBacterial strainen_US
dc.subject.emtreeBroth dilutionen_US
dc.subject.emtreeDrug determinationen_US
dc.subject.emtreeEscherichia colien_US
dc.subject.emtreeFilipendulaen_US
dc.subject.emtreeHigh performance liquid chromatographyen_US
dc.subject.emtreeLimit of detectionen_US
dc.subject.emtreeLimit of quantitationen_US
dc.subject.emtreeMinimum inhibitory concentrationen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreeSolvent extractionen_US
dc.subject.emtreeStaphylococcus aureusen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeValidation processen_US
dc.subject.emtreeAcetoneen_US
dc.subject.emtreeAciden_US
dc.subject.emtreeAlcoholen_US
dc.subject.emtreeGallic acid derivativeen_US
dc.subject.emtreeMethanolen_US
dc.subject.emtreeNatural producten_US
dc.subject.emtreePhenolen_US
dc.subject.emtreeStictic aciden_US
dc.subject.emtreeUnclassified drugen_US
dc.subject.emtreeUsnic aciden_US
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