Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes

Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29963

Title:	Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes
Authors:	Koz, Gamze Koz, Ömer Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü. Coşkun, Necdet B-1200-2012 7004177880
Keywords:	Chemistry Amino alcohol catalyst Enantioselective conjugate addition 2-iminochromene Nitromethane Asymmetric conjugate addition Michael addition Privileged structures Efficient Derivatives Nitroalkanes Apoptosis Chromene Salicylaldehydes Malononitrile
Issue Date:	22-Apr-2016
Publisher:	Taylor & Francis
Citation:	Koz, G. vd. (2016). "Enantioselective synthesis of 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles from 2-iminochromenes". Synthetic Communications, 46(10), 909-915.
Abstract:	A series of medicinally important 2-amino-4-(nitromethyl)-4H-chromene-3-carbonitriles were synthesized using enantioselective conjugate addition of nitromethane to 2-iminochromenes. The reactions were performed using L8-Cu (II) catalytic system and moderate to good enantioselectivities (62-88%) and yields (66-96%) were obtained.
URI:	https://doi.org/10.1080/00397911.2016.1177728 https://www.tandfonline.com/doi/full/10.1080/00397911.2016.1177728 http://hdl.handle.net/11452/29963
ISSN:	0039-7911 1532-2432
Appears in Collections:	Scopus Web of Science

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