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Title: | Antibiotic susceptibility, antibacterial activity and characterisation of Enterococcus faecium strains isolated from breast milk |
Authors: | Kıvanç, Merih Yiğit, Tülay Uludağ Üniversitesi/Tıp Fakültesi/Göz Hastalıkları Anabilim Dalı. 0000-0002-0932-6977 Kıvanç, Sertaç Argün AAH-6518-2021 47861204900 |
Keywords: | Research & experimental medicine Enterococcus faecium Breast milk Probiotics Antibacterial activity Ocular surface Lactic-acid bacteria Dairy-products Molecular characterization Virulence determinants Biofilm formation Faecalis Cheese Infantproteolysis Food |
Issue Date: | 18-May-2016 |
Publisher: | Spandidos |
Citation: | Kıvanç, S. A. vd. (2016). "Antibiotic susceptibility, antibacterial activity and characterisation of Enterococcus faecium strains isolated from breast milk". Experimental and Therapeutic Medicine, 12(3), 1732-1740. |
Abstract: | Enterococci, which have useful biotechnological applications, produce bacteriocins, including those that exert anti-Listerial activity. The present study aimed to determine the antibiotic susceptibility patterns and antimicrobial activity of Enterococcus faecium strains isolated from human breast milk. The strains were identified using carbohydrate fermentation tests and ribotyping. Subsequently, the antibacterial activity of the isolates was investigated, and the quantities of lactic acid and hydrogen peroxide produced, and the proteolytic activity of E. faecium, were determined. In addition, biofilm formation by E. faecium strains was assessed. E. faecium strains exhibited antimicrobial activity against food-borne and clinical bacterial isolates. Furthermore, following 24 h incubation, the tested strains exhibited resistance to a pH range of 2.0-9.5 and tolerance of bile acid, lysozyme activity and phenol. Supernatants of the E. faecium TM13, TM15, TM17 and TM18 strains were shown to be effective against Listeria monocytogenes, and were also resistant to heat. Further studies are required in order to determine whether certain strains of E. faecium may be used for the development of novel antibacterial agents. |
URI: | https://doi.org/10.3892/etm.2016.3545 https://www.spandidos-publications.com/10.3892/etm.2016.3545 http://hdl.handle.net/11452/31392 |
ISSN: | 1792-0981 1792-1015 |
Appears in Collections: | Scopus Web of Science |
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