Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/32100
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dc.contributor.authorBörekçi, Şermin-
dc.contributor.authorDemir, Tunçalp-
dc.contributor.authorUygun, Melahat-
dc.contributor.authorYıldırım, Nurhayat-
dc.date.accessioned2023-03-31T05:59:41Z-
dc.date.available2023-03-31T05:59:41Z-
dc.date.issued2017-03-
dc.identifier.citationBörekçi, S. vd. (2017). ''A simple measure to assess hyperinflation and air trapping: 1-forced expiratory volume in three second / forced vital capacity''. Balkan Medical Journal, 34(2), 113-118.tr_TR
dc.identifier.issn2146-3123-
dc.identifier.issn2146-3131-
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.2015.0857-
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/607882-
dc.identifier.urihttp://hdl.handle.net/11452/32100-
dc.description.abstractBackground: Several recent studies have suggested that 1 minus-forced expiratory volume expired in 3 seconds / forced vital capacity (1-FEV3/FVC) may be an indicator of distal airway obstruction and a promising measure to evaluate small airways dysfunction. Aims: To investigate the associations of 1-FEV3/FVC with the spirometric measures and lung volumes that assess small airways dysfunction and reflects hyperinflation and air trapping. Study Design: Retrospective cross-sectional study. Methods: Retrospective assessment of a total of 1110 cases who underwent body plethysmographic lung volume estimations between a time span from 2005 to 2012. Patients were assigned into two groups: firstly by FEV1/FVC (FEV1/FVC <70% vs. FEV1/FVC >= 70%); secondly by FEV3/FVC < lower limits of normal (LLN) (FEV3/FVC < LLN vs. FEV3/FVC >= LLN). Spirometric indices and lung volumes measured by whole-body plethysmography were compared in groups. Also the correlation of spirometric indices with measured lung volumes were assessed in the whole-study population and in subgroups stratified according to FEV1/FVC and FEV3/FVC. Results: Six hundred seven (54.7%) were male and 503 (45.3%) were female, with a mean age of 52.5 +/- 15.6 years. Mean FEV3/FVC and 1-FEV3/FVC were 87.05%, 12.95%, respectively. The mean 1-FEV3/FVC was 4.9% in the FEV1/FVC >= 70% group (n=644) vs. 24.1% in the FEV1/FVC < 70% group (n=466). A positive correlation was found between 1-FEV3/FVC and residual volume (r=0.70; p<0.0001), functional residual capacity-pleth (r=0.61; p<0.0001), and total lung capacity (r=0.47; p<0.0001). 1-FEV3/FVC was negatively correlated with forced expiratory flow25-75 (r=0.84; p<0.0001). The upper limit of 95% confidence interval for 1-FEV3/FVC was 13.7%. 1-FEV3/FVC showed significant correlations with parameters of air trapping and hyperinflation measured by whole-body plethysmography. Importantly, these correlations were higher in study participants with FEV1/FVC <70% or FEV3/FVC < LLN compared to those with FEV1/FVC >= 70% or FEV3/FVC >= LLN, respectively. Conclusion: 1-FEV3/FVC can be easily calculated from routine spirometric measurements. 1-FEV3/FVC is a promising marker of air trapping and hyperinflation. We suggest that 1-FEV3/FVC is complementary to FEV1/FVC and recommend clinicians to routinely report and evaluate together with FEV1/FVC during spirometry.en_US
dc.language.isoenen_US
dc.publisherGalenos Yayınevien_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectGeneral & internal medicineen_US
dc.subject1-FEV3/FVCen_US
dc.subjectHyperinflationen_US
dc.subjectSpirometryen_US
dc.subjectFlow obstructionen_US
dc.subjectValuesen_US
dc.subjectStandardizationen_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCross-sectional studiesen_US
dc.subject.meshFemaleen_US
dc.subject.meshForced expiratory volumeen_US
dc.subject.meshHumansen_US
dc.subject.meshLungen_US
dc.subject.meshMaleen_US
dc.subject.meshLung volume measurementsen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshRespiratory function testsen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshSeverity of illness indexen_US
dc.subject.meshSpirometryen_US
dc.subject.meshStatisticsen_US
dc.subject.meshNonparametricen_US
dc.subject.meshVital capacityen_US
dc.subject.meshWeights and measuresen_US
dc.titleA simple measure to assess hyperinflation and air trapping: 1-forced expiratory volume in three second / forced vital capacityen_US
dc.typeArticleen_US
dc.identifier.wos000400660600004tr_TR
dc.identifier.scopus2-s2.0-85016407053tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.tr_TR
dc.identifier.startpage113tr_TR
dc.identifier.endpage118tr_TR
dc.identifier.volume34tr_TR
dc.identifier.issue2tr_TR
dc.relation.journalBalkan Medical Journalen_US
dc.contributor.buuauthorDilektaşlı, Aslı Görek-
dc.relation.collaborationYurt içitr_TR
dc.indexed.trdizinTrDizintr_TR
dc.identifier.pubmed28418337tr_TR
dc.subject.wosMedicine, general & internalen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid36466376600tr_TR
dc.subject.scopusSpirometry; Forced Expiratory Volume; Lung Functionen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeBody plethysmographyen_US
dc.subject.emtreeConfidence intervalen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCross-sectional studyen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeForced expiratory flowen_US
dc.subject.emtreeForced expiratory volumeen_US
dc.subject.emtreeForced vital capacityen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHyperinflationen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeResidual volumeen_US
dc.subject.emtreeSpirometryen_US
dc.subject.emtreeStudy designen_US
dc.subject.emtreeTotal lung capacityen_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeForced expiratory volumeen_US
dc.subject.emtreeLungen_US
dc.subject.emtreeLung function testen_US
dc.subject.emtreeLung volumeen_US
dc.subject.emtreeNonparametric testen_US
dc.subject.emtreePathophysiologyen_US
dc.subject.emtreePhysiologyen_US
dc.subject.emtreeProceduresen_US
dc.subject.emtreeNetrospective studyen_US
dc.subject.emtreeSeverity of illness indexen_US
dc.subject.emtreeSpirometryen_US
dc.subject.emtreeStandarden_US
dc.subject.emtreeStandardsen_US
dc.subject.emtreeVital capacityen_US
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