Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/32307
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dc.date.accessioned2023-04-11T07:44:55Z-
dc.date.available2023-04-11T07:44:55Z-
dc.date.issued2016-02-18-
dc.identifier.citationAnıl, A. vd. (2016). "Comparison of postoperative analgesic efficacy of intraoperative single-dose intravenous administration of dexketoprofen trometamol and diclofenac sodium in laparoscopic cholecystectomy". Journal of Clinical Anesthesia, 32, 127-133.en_US
dc.identifier.issn0952-8180-
dc.identifier.issn1873-4529-
dc.identifier.urihttps://doi.org/10.1016/j.jclinane.2016.02.020-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0952818016001483-
dc.identifier.urihttp://hdl.handle.net/11452/32307-
dc.description.abstractStudy objective: The aim of this study is to compare the effects of intravenous single-dose dexketoprofen trometamol and diclofenac sodium 30 minutes before the end of the surgery on relief of postoperative pain in patients undergoing laparoscopic cholecystectomy. Design: A randomized fashion. Setting and patients: Sixty (American Society of Anesthesiologist class I-II) patients undergoing laparoscopic cholecystectomy were divided into 2 groups. Intervention: Patients in group DT received 50 mg dexketoprofen trometamol, whereas patients in group DS received 75 mg diclofenac sodium, intravenously 30 minutes before the end of surgery. Measurements: Postoperative pain intensity, morphine consumption with patient-controlled analgesia, time to first analgesic requirement, complications, rescue analgesic (intravenous tenoxicam 20 mg) requirement, and duration of hospital stay were recorded. Main results: Postoperative pain visual analog scale scores were similar in the follow-up periods (P>.05). Patient-controlled analgesia morphine consumption was significantly less in group DT compared with group DS in all postoperative follow-up periods (2 and 4 hours: P <.01; 8, 12, 18, and 24 hours: P<.001). In the postoperative period, the first analgesic requirement time was significantly longer in group DT compared with group DS (P <.01). In addition, the number of patients requiring rescue analgesic was higher in group DS compared with group DT (P <.01). Other follow-up parameters were similar. Conclusion: In our study, administration of intravenous single-dose dexketoprofen trometamol 30 minutes before the end of surgery provided effective analgesia with reduced consumption of opioids and requirement for rescue analgesic compared with diclofenac sodium in patients undergoing laparoscopic cholecystectomy. For this reason, we believe that, as a part of multimodal analgesia, dexketoprofen trometamol provides more effective analgesia than diclofenac sodium in patients undergoing laparoscopic cholecystectomy.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnesthesiologyen_US
dc.subjectAnalgesic efficacyen_US
dc.subjectDexketoprofen trometamolen_US
dc.subjectDiclofenac sodiumen_US
dc.subjectLaparoscopic cholecystectomyen_US
dc.subjectPatient-controlled analgesiaen_US
dc.subjectRandomized controlled-trialen_US
dc.subjectIntramuscular dexketoprofenen_US
dc.subjectPreemptive analgesiaen_US
dc.subjectClinical-trialen_US
dc.subjectPainen_US
dc.subjectSurgeryen_US
dc.subjectKetoprofenen_US
dc.subjectPlaceboen_US
dc.subject.meshAdolescenten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshAnalgesiaen_US
dc.subject.meshAnti-Inflammatory agents, non-steroidalen_US
dc.subject.meshCholecystectomy, laparoscopicen_US
dc.subject.meshDiclofenacen_US
dc.subject.meshFemaleen_US
dc.subject.meshHumansen_US
dc.subject.meshInjections, intravenousen_US
dc.subject.meshIntraoperative careen_US
dc.subject.meshKetoprofenen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPain, postoperativeen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshTromethamineen_US
dc.subject.meshYoung adulten_US
dc.titleComparison of postoperative analgesic efficacy of intraoperative single-dose intravenous administration of dexketoprofen trometamol and diclofenac sodium in laparoscopic cholecystectomyen_US
dc.typeArticleen_US
dc.identifier.wos000378365600028tr_TR
dc.identifier.scopus2-s2.0-84964434750tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji ve Reanimasyon Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-3019-581Xtr_TR
dc.identifier.startpage127tr_TR
dc.identifier.endpage133tr_TR
dc.identifier.volume32tr_TR
dc.relation.journalJournal of Clinical Anesthesiaen_US
dc.contributor.buuauthorAnıl, Ali-
dc.contributor.buuauthorKaya, Fatma Nur-
dc.contributor.buuauthorYavaşcaoğlu, Belgin-
dc.contributor.buuauthorEfe, Esra Mercanoğlu-
dc.contributor.buuauthorTürker, Gürkan-
dc.contributor.buuauthorDemirci, Abdurrahman-
dc.contributor.researcheridAAI-6642-2021tr_TR
dc.contributor.researcheridAAI-7914-2021tr_TR
dc.contributor.researcheridAAI-8213-2021tr_TR
dc.identifier.pubmed27290960tr_TR
dc.subject.wosAnesthesiologyen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ3en_US
dc.contributor.scopusid55899362600tr_TR
dc.contributor.scopusid7003619647tr_TR
dc.contributor.scopusid6602742300tr_TR
dc.contributor.scopusid57188989249tr_TR
dc.contributor.scopusid7003400116tr_TR
dc.contributor.scopusid55898600900tr_TR
dc.subject.scopusAntalgic Agent; Postoperative Pain; Acetaminophen Glucuronideen_US
dc.subject.emtreeDexketoprofenen_US
dc.subject.emtreeDiclofenacen_US
dc.subject.emtreeMorphineen_US
dc.subject.emtreeTenoxicamen_US
dc.subject.emtreeDexketoprofenen_US
dc.subject.emtreeDiclofenacen_US
dc.subject.emtreeKetoprofenen_US
dc.subject.emtreeNonsteroid antiinflammatory agenten_US
dc.subject.emtreeTrometamolen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBradycardiaen_US
dc.subject.emtreeComparative effectivenessen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug efficacyen_US
dc.subject.emtreeDrug useen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeFollow upen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeHypotensionen_US
dc.subject.emtreeIntraoperative perioden_US
dc.subject.emtreeLaparoscopic cholecystectomyen_US
dc.subject.emtreeLength of stayen_US
dc.subject.emtreeMajor clinical studyen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeNausea and vomitingen_US
dc.subject.emtreePain intensityen_US
dc.subject.emtreePatient controlled analgesiaen_US
dc.subject.emtreePostoperative analgesiaen_US
dc.subject.emtreePostoperative painen_US
dc.subject.emtreePostoperative perioden_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeRandomized controlled trialen_US
dc.subject.emtreeSingle drug doseen_US
dc.subject.emtreeTreatment outcomeen_US
dc.subject.emtreeVisual analog scaleen_US
dc.subject.emtreeAdolescenten_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAnalgesiaen_US
dc.subject.emtreeAnalogs and derivativesen_US
dc.subject.emtreeComparative studyen_US
dc.subject.emtreeIntravenous drug administrationen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreePain, postoperativeen_US
dc.subject.emtreePeroperative careen_US
dc.subject.emtreeProceduresen_US
dc.subject.emtreeYoung adulten_US
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