The effect of deslorelin acetate in the treatment of persistent urinary incontinence after operation of ectopic ureter in a golden retriever bitch

Abstract

In this report, deslorelin acetate (suprelorin) implant, a GnRH depot analogue, was used for the first time in postoperatively observed urinary incontinence treatment of one year old female Golden Retriever puppy which came to our hospital with urinary incontinence complaint, diagnosed with left unilateral extramural ectopic ureter, treated for her ectopic ureter with ureteroneocystostomy operation and undergone ovariohysterectomy operation at the same time. In the examination at the end of eight months of postoperative period, it was observed that urinary incontinence which was thought to be due to urinary sphincter deficiency following the ectopic ureter surgery has been completely disappeared. The positive effect of deslorelin acetate on the treatment of urinary incontinence after ovariohysterectomy, which was reported in the literature in a limited number, was also found to be effective in the treatment of urinary sphincter deficiency, which was frequently observed following the ectopic ureter surgery.

Bu raporda üriner inkontinens şikayeti ile hastanemize getirilen ve sol unilateral ekstramural ektopik üreter tanısı konarak üreteroneo- sistostomi operasyonu ile ektopik üreteri onarılan ve aynı anda ovariohisterektomi operasyonu da geçiren 1 yaşlı, dişi Golden Retriever yavrusunda gözlenen postoperatif üriner inkontinensin tedavisinde ilk kez kullanılan GnRH depo analoğu deslorelin asetat(suprelorin) implantının etkinliği ele alındı. Postoperatif sekizinci ayda yapılan muayenelerde ektopik üreter operasyonunu takiben üriner sfinkter yetmezliği kaynaklı olduğu düşünülen üriner inkontinensin tamamen ortadan kalktığı gözlendi. Ovariohisterektomi sonrası üriner inkontinens tedavisindeki etkinliği önceden bilinen deslorelin asetatın, ektopik üreter operasyonunu takiben sıklıkla gözlenen üriner sfinkter yetmezliğinde de etkili olduğu düşünüldü.