Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/34577
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dc.date.accessioned2023-10-26T06:47:22Z-
dc.date.available2023-10-26T06:47:22Z-
dc.date.issued2020-
dc.identifier.citationÖzçakır, Ş. vd. (2020). "COPD and osteoporosis: Associated factors in patients treated with ınhaled corticosteroids". International Journal of COPD, 15, 2441-2448.tr_TR
dc.identifier.issn1178-2005-
dc.identifier.issn11769106-
dc.identifier.urihttps://doi.org/10.2147/COPD.S274728-
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553256/pdf/copd-15-2441.pdf-
dc.identifier.urihttp://hdl.handle.net/11452/34577-
dc.description.abstractPurpose: Osteoporosis is a systemic skeletal disease with a consequent increase in fractures rates. Osteoporosis may be primary which is related with normal aging, or secondary which occurs in the presence of an underlying disease or medication. Osteoporosis is one of the significant comorbidities in chronic obstructive pulmonary disease (COPD). In this study, we aimed to investigate the presence of osteoporosis and the influencing factors in COPD patients. Patients and Methods: This is a two-group comparison study that was conducted among 30 COPD patients on inhaled corticosteroid (ICS) and 33 controls. It was conducted in the outpatient clinics at the Departments of Physical Medicine and Rehabilitation and Pulmonary Diseases in Bursa Uludag University Hospital, a tertiary reference center, in the northwest region of Turkey. For both groups, demographic variables, osteoporosis risk questioning, body mass index (BMI), bone mineral density (BMD), biochemical blood tests, vertebral fractures on lumbar and thoracic x-rays were recorded. COPD patients were also evaluated for lung functions via spirometry. Results: Thirty patients with COPD (Group 1) and 33 controls (Group 2) were included in the study. Comparing the demographic and biochemical data, no difference was found between the groups except smoking (pack/year) (p<0.001) and erythrocyte sedimentation rate (p<0.001), which were significantly high in COPD group. BMD in the COPD group was significantly lower in both hip and lumbar regions compared with the controls. There were significant correlations between L2 BMD values and pulmonary function tests. BMI was significantly low in osteoporotic COPD patients when compared with the non-osteoporotic COPD patients (p=0.002). Conclusion: In patients with COPD using inhaled corticosteroids, BMD was significantly low compared with the controls. Osteoporotic COPD patients had significantly lower BMI than non-osteoporotic. These findings suggest that pulmonary dysfunction and low BMI are associated with osteoporosis in COPD patients.en_US
dc.language.isoenen_US
dc.publisherDove Medical Pressen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.rightsAtıf Gayri Ticari Türetilemez 4.0 Uluslararasıtr_TR
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectRespiratory systemen_US
dc.subjectBMDen_US
dc.subjectOsteoporosisen_US
dc.subjectCOPDen_US
dc.subjectBMIen_US
dc.subject.meshAbsorptiometry, photonen_US
dc.subject.meshAdrenal cortex hormonesen_US
dc.subject.meshBone densityen_US
dc.subject.meshHumansen_US
dc.subject.meshOsteoporosisen_US
dc.subject.meshPulmonary disease, chronic obstructiveen_US
dc.subject.meshTurkeyen_US
dc.titleCOPD and osteoporosis: Associated factors in patients treated with ınhaled corticosteroidsen_US
dc.typeArticleen_US
dc.identifier.wos000577480500001tr_TR
dc.identifier.scopus2-s2.0-85092222676tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı.tr_TR
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.departmentBursa Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0003-0851-3620tr_TR
dc.identifier.startpage2441tr_TR
dc.identifier.endpage2448tr_TR
dc.identifier.volume15tr_TR
dc.relation.journalInternational Journal of COPDen_US
dc.contributor.buuauthorÖzçakır, Şüheda-
dc.contributor.buuauthorSığırlı, Deniz-
dc.contributor.buuauthorUrsavaş, Ahmet-
dc.contributor.buuauthorUzaslan, Esra-
dc.contributor.researcheridAAH-5375-2021tr_TR
dc.contributor.researcheridAAA-7472-2021tr_TR
dc.contributor.researcheridAAI-3169-2021tr_TR
dc.contributor.researcheridAAI-1004-2021tr_TR
dc.identifier.pubmed33116459tr_TR
dc.subject.wosRespiratory systemen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ2en_US
dc.contributor.scopusid15757855500tr_TR
dc.contributor.scopusid24482063400tr_TR
dc.contributor.scopusid8329319900tr_TR
dc.contributor.scopusid8761653500tr_TR
dc.subject.scopusChronic obstructive lung disease; Osteoporosis; Bone densityen_US
dc.subject.emtreeAlkaline phosphataseen_US
dc.subject.emtreeCalciumen_US
dc.subject.emtreeCorticosteroiden_US
dc.subject.emtreeLiothyronineen_US
dc.subject.emtreePhosphorusen_US
dc.subject.emtreeThyrotropinen_US
dc.subject.emtreeThyroxineen_US
dc.subject.emtreeCorticosteroiden_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeAgeen_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeAlkaline phosphatase blood levelen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBody heighten_US
dc.subject.emtreeBody massen_US
dc.subject.emtreeBody weighten_US
dc.subject.emtreeBone densitometryen_US
dc.subject.emtreeBone densityen_US
dc.subject.emtreeCalcium blood levelen_US
dc.subject.emtreeChronic obstructive lung diseaseen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeComorbidityen_US
dc.subject.emtreeComparative studyen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeCorticosteroid therapyen_US
dc.subject.emtreeDisease associationen_US
dc.subject.emtreeDual energy x ray absorptiometryen_US
dc.subject.emtreeErythrocyte sedimentation rateen_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeForced expiratory volumeen_US
dc.subject.emtreeForced vital capacityen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLiothyronine blood levelen_US
dc.subject.emtreeLumbar spineen_US
dc.subject.emtreeLung functionen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeOsteoporosisen_US
dc.subject.emtreeOutpatient departmenten_US
dc.subject.emtreePeak expiratory flowen_US
dc.subject.emtreePhosphate blood levelen_US
dc.subject.emtreeRisken_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeSmokingen_US
dc.subject.emtreeSpine fractureen_US
dc.subject.emtreeSpine radiographyen_US
dc.subject.emtreeSpirometryen_US
dc.subject.emtreeThoracic spineen_US
dc.subject.emtreeThyrotropin blood levelen_US
dc.subject.emtreeThyroxine blood levelen_US
dc.subject.emtreeTurkey (republic)en_US
dc.subject.emtreeChronic obstructive lung diseaseen_US
dc.subject.emtreeOsteoporosisen_US
dc.subject.emtreePhoton absorptiometryen_US
dc.subject.emtreeTurkey (bird)en_US
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