Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/34776
Title: Identification of the synthetic cannabinoid N-(2-phenyl-propan-2-yl)-1-(4-cyanobutyl)-1H-indazole-3-carboxamide (CUMYL-4CN-BINACA) in a herbal mixture product
Authors: Kapucu, Hicran
Altun, Neslihan Çallı
Eren, Bülent
Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü.
Ölmez, Nevin Arıkan
AAH-6337-2021
57194701904
Keywords: Toxicology
Synthetic cannabinoid
CUMYL-4CN-BINACA
Herbal mixture
One and two dimensional NMR
ATR-FT-IR
Drugs
Issue Date: 25-Jun-2017
Publisher: Springer
Citation: Ölmez, N. A. vd. (2018). ''Identification of the synthetic cannabinoid N-(2-phenyl-propan-2-yl)-1-(4-cyanobutyl)-1H-indazole-3-carboxamide (CUMYL-4CN-BINACA) in a herbal mixture product''. Forensic Toxicology, 36(1), 192-199.
Abstract: We were the first to detect N-(2-phenylpropan-2-yl)-1-(4-cyanobutyl)-1H-indazole-3-carboxamide (common name CUMYL-4CN-BINACA) as a new synthetic cannabinoid, on the illegal market in Bursa, Turkey. To elucidate the chemical structure, the dried herbal mixture was extracted with methanol. The extract was purified by column chromatography. Pure compound was analyzed by gas chromatography-mass spectrometry (GC-MS), attenuated total reflection Fourier-transform infrared spectroscopy (FT-IR), and one- and two-dimensional nuclear magnetic resonance (NMR) spectroscopy. The GC-MS, FT-IR and H-1 and C-13 NMR spectra of the compound coincided well with the reference data. All protons and carbons were assigned by their couplings and correlations observed in H-1-H-1 correlation spectroscopy, H-1-C-13 heteronuclear multiple bond correlation, and H-1-C-13 heteronuclear single quantum coherence spectra. On the basis of the spectral data, the compound was identified as CUMYL-4CN-BINACA. Herewith, we report analytical characteristics of CUMYL-4CN-BINACA enabling its (and possible analogues thereof) determination in criminal seizures.
URI: https://doi.org/10.1007/s11419-017-0372-y
https://link.springer.com/article/10.1007/s11419-017-0372-y
http://hdl.handle.net/11452/34776
ISSN: 1860-8965
1860-8973
Appears in Collections:Scopus
Web of Science

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