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http://hdl.handle.net/11452/34986
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DC Field | Value | Language |
---|---|---|
dc.contributor.author | Levendusky, Mark C. | - |
dc.contributor.author | Millington, William R. | - |
dc.date.accessioned | 2023-11-23T06:24:51Z | - |
dc.date.available | 2023-11-23T06:24:51Z | - |
dc.date.issued | 2004-12-10 | - |
dc.identifier.citation | Göktalay, G. vd. (2004). “Muscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociception”. Brain Research , 1029(1), 124-130. | en_US |
dc.identifier.issn | 0006-8993 | - |
dc.identifier.uri | https://doi.org/10.1016/j.brainres.2004.09.029 | - |
dc.identifier.uri | https://www.sciencedirect.com/science/article/pii/S0006899304015707 | - |
dc.identifier.uri | http://hdl.handle.net/11452/34986 | - |
dc.description.abstract | This study investigated whether the lateral hypothalamus (LH) contributes to the depressor response evoked by somato-visceral nociception. Lidocame (2%; 0.1, 0.3 or 1.0 mul) or muscimol (0.34 nmol; 0.5 mul) was microinjected into the rostral LH of halothane-anesthetized rats bilaterally and somato-visceral nociception was induced 2 min later by injecting 5% acetic acid (0.5 ml) intraperitoneally. Lidocaine and muscimol inhibited the hypotension and bradycardia caused by somato-visceral nociception significantly without affecting cardiovascular function in normotensive animals. | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Neurosciences and neurology | en_US |
dc.subject | Lateral hypothalamus | en_US |
dc.subject | Visceral nociception | en_US |
dc.subject | Pain | en_US |
dc.subject | GABA receptor | en_US |
dc.subject | Muscimol | en_US |
dc.subject | Cardiovascular regulation | en_US |
dc.subject | Midbrain periaqueductal gray | en_US |
dc.subject | Anterior hypothalamus | en_US |
dc.subject | Efferent projections | en_US |
dc.subject | Fos | en_US |
dc.subject | Area | en_US |
dc.subject | Immunoreactivity | en_US |
dc.subject | Organization | en_US |
dc.subject | Stimulation | en_US |
dc.subject | Nucleus | en_US |
dc.subject | Neurons | en_US |
dc.subject.mesh | Animals | en_US |
dc.subject.mesh | Bradycardia | en_US |
dc.subject.mesh | Cardiovascular physiology | en_US |
dc.subject.mesh | GABA agonists | en_US |
dc.subject.mesh | Homocysteine | en_US |
dc.subject.mesh | Hypotension | en_US |
dc.subject.mesh | Hypothalamic area, lateral | en_US |
dc.subject.mesh | Male | en_US |
dc.subject.mesh | Microinjections | en_US |
dc.subject.mesh | Muscimol | en_US |
dc.subject.mesh | Pain | en_US |
dc.subject.mesh | Rats | en_US |
dc.subject.mesh | Rats, sprague-dawley | en_US |
dc.title | Muscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociception | en_US |
dc.type | Article | en_US |
dc.identifier.wos | 000225481700015 | tr_TR |
dc.identifier.scopus | 2-s2.0-7744237862 | tr_TR |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi | tr_TR |
dc.contributor.department | Uludağ Üniversitesi/Tıp Fakültesi/Tıbbi Farmakoloji Anabilim Dalı. | tr_TR |
dc.contributor.orcid | 0000-0001-6261-4233 | tr_TR |
dc.identifier.startpage | 124 | tr_TR |
dc.identifier.endpage | 130 | tr_TR |
dc.identifier.volume | 1029 | tr_TR |
dc.identifier.issue | 1 | tr_TR |
dc.relation.journal | Brain Research | en_US |
dc.contributor.buuauthor | Göktalay, Gökhan | - |
dc.contributor.researcherid | AAH-1448-2021 | en_US |
dc.relation.collaboration | Yurt dışı | en_US |
dc.identifier.pubmed | 15533324 | en_US |
dc.subject.wos | Neurosciences | en_US |
dc.indexed.wos | SCIE | en_US |
dc.indexed.scopus | Scopus | en_US |
dc.indexed.pubmed | PubMed | en_US |
dc.wos.quartile | Q2 | en_US |
dc.contributor.scopusid | 6508023759 | en_US |
dc.subject.scopus | Periaqueductal Gray; Animals; Escape Reaction | en_US |
dc.subject.emtree | Animal experiment | en_US |
dc.subject.emtree | Animal model | en_US |
dc.subject.emtree | Article | en_US |
dc.subject.emtree | Bradycardia | en_US |
dc.subject.emtree | Cardiovascular function | en_US |
dc.subject.emtree | Controlled study | en_US |
dc.subject.emtree | Drug effect | en_US |
dc.subject.emtree | Evoked somatosensory response | en_US |
dc.subject.emtree | Hypotension | en_US |
dc.subject.emtree | Hypothalamus | en_US |
dc.subject.emtree | Male | en_US |
dc.subject.emtree | Microinjection | en_US |
dc.subject.emtree | Nociception | en_US |
dc.subject.emtree | Nonhuman | en_US |
dc.subject.emtree | Priority journal | en_US |
dc.subject.emtree | Rat | en_US |
dc.subject.emtree | 4 aminobutyric acid a receptor stimulating agent | en_US |
dc.subject.emtree | Acetic acid | en_US |
dc.subject.emtree | Lidocaine | en_US |
dc.subject.emtree | Muscimol | en_US |
Appears in Collections: | Scopus Web of Science |
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