Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/34986
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dc.contributor.authorLevendusky, Mark C.-
dc.contributor.authorMillington, William R.-
dc.date.accessioned2023-11-23T06:24:51Z-
dc.date.available2023-11-23T06:24:51Z-
dc.date.issued2004-12-10-
dc.identifier.citationGöktalay, G. vd. (2004). “Muscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociception”. Brain Research , 1029(1), 124-130.en_US
dc.identifier.issn0006-8993-
dc.identifier.urihttps://doi.org/10.1016/j.brainres.2004.09.029-
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0006899304015707-
dc.identifier.urihttp://hdl.handle.net/11452/34986-
dc.description.abstractThis study investigated whether the lateral hypothalamus (LH) contributes to the depressor response evoked by somato-visceral nociception. Lidocame (2%; 0.1, 0.3 or 1.0 mul) or muscimol (0.34 nmol; 0.5 mul) was microinjected into the rostral LH of halothane-anesthetized rats bilaterally and somato-visceral nociception was induced 2 min later by injecting 5% acetic acid (0.5 ml) intraperitoneally. Lidocaine and muscimol inhibited the hypotension and bradycardia caused by somato-visceral nociception significantly without affecting cardiovascular function in normotensive animals.en_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectNeurosciences and neurologyen_US
dc.subjectLateral hypothalamusen_US
dc.subjectVisceral nociceptionen_US
dc.subjectPainen_US
dc.subjectGABA receptoren_US
dc.subjectMuscimolen_US
dc.subjectCardiovascular regulationen_US
dc.subjectMidbrain periaqueductal grayen_US
dc.subjectAnterior hypothalamusen_US
dc.subjectEfferent projectionsen_US
dc.subjectFosen_US
dc.subjectAreaen_US
dc.subjectImmunoreactivityen_US
dc.subjectOrganizationen_US
dc.subjectStimulationen_US
dc.subjectNucleusen_US
dc.subjectNeuronsen_US
dc.subject.meshAnimalsen_US
dc.subject.meshBradycardiaen_US
dc.subject.meshCardiovascular physiologyen_US
dc.subject.meshGABA agonistsen_US
dc.subject.meshHomocysteineen_US
dc.subject.meshHypotensionen_US
dc.subject.meshHypothalamic area, lateralen_US
dc.subject.meshMaleen_US
dc.subject.meshMicroinjectionsen_US
dc.subject.meshMuscimolen_US
dc.subject.meshPainen_US
dc.subject.meshRatsen_US
dc.subject.meshRats, sprague-dawleyen_US
dc.titleMuscimol injection into the lateral hypothalamus inhibits the hypotension and bradycardia caused by somato-visceral nociceptionen_US
dc.typeArticleen_US
dc.identifier.wos000225481700015tr_TR
dc.identifier.scopus2-s2.0-7744237862tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Tıbbi Farmakoloji Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0001-6261-4233tr_TR
dc.identifier.startpage124tr_TR
dc.identifier.endpage130tr_TR
dc.identifier.volume1029tr_TR
dc.identifier.issue1tr_TR
dc.relation.journalBrain Researchen_US
dc.contributor.buuauthorGöktalay, Gökhan-
dc.contributor.researcheridAAH-1448-2021en_US
dc.relation.collaborationYurt dışıen_US
dc.identifier.pubmed15533324en_US
dc.subject.wosNeurosciencesen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.wos.quartileQ2en_US
dc.contributor.scopusid6508023759en_US
dc.subject.scopusPeriaqueductal Gray; Animals; Escape Reactionen_US
dc.subject.emtreeAnimal experimenten_US
dc.subject.emtreeAnimal modelen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBradycardiaen_US
dc.subject.emtreeCardiovascular functionen_US
dc.subject.emtreeControlled studyen_US
dc.subject.emtreeDrug effecten_US
dc.subject.emtreeEvoked somatosensory responseen_US
dc.subject.emtreeHypotensionen_US
dc.subject.emtreeHypothalamusen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMicroinjectionen_US
dc.subject.emtreeNociceptionen_US
dc.subject.emtreeNonhumanen_US
dc.subject.emtreePriority journalen_US
dc.subject.emtreeRaten_US
dc.subject.emtree4 aminobutyric acid a receptor stimulating agenten_US
dc.subject.emtreeAcetic aciden_US
dc.subject.emtreeLidocaineen_US
dc.subject.emtreeMuscimolen_US
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