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http://hdl.handle.net/11452/21165
Başlık: | The effects of a fluoroquinolone on the growth and development of infants |
Yazarlar: | Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Cerrahisi Anabilim Dalı. Gürpınar, Arif Nuri Balkan, Emin Kılıç, Nizamettin Kiriştioğlu, İrfan Doǧruyol, Hasan AAI-3656-2021 |
Anahtar kelimeler: | Research & experimental medicine Pharmacology & pharmacy Ciprofloxacin Fluoroquinolones Guinolones Antibacterial drugs Sepsis Neonates Growth Development |
Yayın Tarihi: | 1997 |
Yayıncı: | Cambridge Med Publ |
Atıf: | Gürpınar, A. N. vd. (1997). "The effects of a fluoroquinolone on the growth and development of infants". Journal of International Medical Research, 25(5), 302-306. |
Özet: | Growth and development were monitored for up to 42 months in nine neonates to whom ciprofloxacin, a fluoroquinolone, was given in the neonatal period at a dosage of 20 mg/kg/day. Ciprofloxacin was used only as a 'life-saving' therapy in cases of sepsis produced by bacterial agents resistant to other antibiotics. Two other groups of nine neonates, matched by birth weight and gestational age, were studied as controls: one group with sepsis, which was effectively treated with cefotaxime and a group of healthy neonates. No statistically significant differences in growth and development between the groups were found during follow-up for 42 months. No osteoarticular problems or joint deformities were observed in the ciprofloxacin group. Ciprofloxacin appears to provide a therapeutic option as a 'life-saving' therapy for newborns with sepsis produced by multiply resistant organisms. |
URI: | http://hdl.handle.net/11452/21165 |
ISSN: | 0300-0605 |
Koleksiyonlarda Görünür: | Web of Science |
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