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Başlık: Effects of green tea on serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic rats
Yazarlar: Uludağ Üniversitesi/Fen Edebiyat Fakültesi/Biyoloji Bölümü.
Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.
0000-0002-2593-7196
Taş, Sibel
Sarandöl, Emre
Ziyanok, Sedef
Aslan, Kemal
Dirican, Melahat
AAH-4272-2021
ABE-1716-2020
AAG-6985-2021
ABE-6873-2020
Anahtar kelimeler: Rat
Oxidative stress
Streptozotocin
Diabetes
Green tea
Paraoxonase
Low-density-lipoprotein
Protect ldl
Paraoxonase activity
Lipid-peroxidation
Black tea
Cholesterol level
Oxidative stress
Ldl oxidation
In-vitro
Polyphenols
Nutrition & dietetics
Yayın Tarihi: Ara-2005
Yayıncı: Pergamon-Elsevier Science
Atıf: Taş, S. vd. (2005). "Effects of green tea on serum paraoxonase/arylesterase activities in streptozotocin-induced diabetic rats". Nutrition Research, 25(12), 1061-1074.
Özet: In recent years, green tea has become a subject of interest because of its beneficial effects on human health. The purpose of this study was to determine the effects of green tea on serum paraoxonase/arylesterase activities and lipoprotein oxidizability in streptozotocin-induced diabetic rats (65 mg/kg [intraperitoneal]). Green tea was given in tap water (2%) for 3 and 6 weeks to control (CGT-3w and CGT-6w) and diabetic (DGT-3w and DGT-6w) rats, and they were compared with the control and diabetic groups (D-3w and D-6w), respectively. Serum insulin level was significantly increased in the DGT-6w group; serum lipid and plasma and tissue malondialdehyde levels were reduced in the DGT-3w and DGT-6w groups. Oxidizability of apolipoprotein B-containing lipoprotein fraction was found to be significantly reduced in the DGT-6w group. Serum total antioxidant capacity showed a significant increase in the CGT-6w and DGT-6w groups. Paraoxonase activity was significantly reduced in the D-3w and D-6w groups and increased in the DGT-6w group. We conclude that green tea might have antilryperlipidernic and antioxidative effects and may slow the progression of atherogenesis by reducing oxidation of lipoproteins and preserving paraoxonase activity.
URI: https://doi.org/10.1016/j.nutres.2005.10.001
https://www.sciencedirect.com/science/article/pii/S0271531705002289?via%3Dihub
http://hdl.handle.net/11452/21444
ISSN: 0271-5317
Koleksiyonlarda Görünür:Scopus
Web of Science

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