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Başlık: Interferon-alpha treatment of molluscum contagiosum in a patient with hyperimmunoglobulin E syndrome
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Sağlığı ve Hastalıkları Anabilim Dalı/İmmünoloji Bilim Dalı.
0000-0001-8571-2581
Kılıç, Sara Şebnem
Kılıçbay, Fatih
AAH-1658-2021
34975059200
14021686700
Anahtar kelimeler: Pediatrics
Molluscum contagiosum
Job's syndrome
Interferon-α
Hyperimmunoglobulin E syndrome
Imiquimod
Hyper-ige syndrome
Yayın Tarihi: 2006
Yayıncı: American Academy Pediatrics
Atıf: Kılıç, S. Ş. ve Kılıçbay, F. (2006). ''Interferon-alpha treatment of molluscum contagiosum in a patient with hyperimmunoglobulin E syndrome''. Pediatrics, 117(6), E1253-E1255.
Özet: We report widely disseminated molluscum contagiosum that occurred in a 9-year-old boy secondary to hyperimmunoglobulin E syndrome, a primary immunodeficiency disorder. Cutaneous examination revealed numerous, widespread, skin-colored to translucent, firm, umbilicated papules of varying sizes. They were distributed throughout the perineal and gluteal areas and bilaterally over his lower limbs. A biopsy specimen from his skin lesion demonstrated lobulated epidermal growth that consisted of keratinocytes with large intracytoplasmic eosinophilic inclusion bodies and a central crater. These findings were consistent with the diagnosis of molluscum contagiosum. Many treatments for his skin lesions were ineffective, including physical destruction or manual extrusion of the lesions; cryotherapy; curettage; and topical therapies with phenol, trichloroacetic acid, and imiquimod. The patient was treated successfully with subcutaneous interferon-alpha for 6 months without any adverse effect.
URI: https://doi.org/10.1542/peds.2005-2706
https://pediatrics.aappublications.org/content/117/6/e1253
http://hdl.handle.net/11452/22443
ISSN: 0031-4005
1098-4275
Koleksiyonlarda Görünür:Scopus
Web of Science

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