1. Açık Erişim@BUU
  2. İndeksli Yayınlar
  3. Web of Science
Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/22452
Title: Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Nefroloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Farmakoloji ve Klinik Farmakoloji Anabilim Dalı.
İlçol, Yeşim Özarda
Dönmez, Osman
Yavuz, Mahmut
Dilek, Kamil
Yurtkuran, Mustafa
Ulus, İsmail Hakkı
AAL-8873-2021
D-5340-2015
AAA-8778-2021
35741320500
19033971800
7006244754
56005080200
7003389525
7004271086
Keywords: Choline
Phospholipid-bound choline
End stage renal disease
CAPD
Peritoneal dialysis
Rat corpus striatum
Acetylcholine-release
Parenteral-nutrition
Tyrosine-Hydroxylase
Plasma choline
Brain
Metabolism
Deficiency
Transport
Cytidine
Liver
Medical laboratory technology
Issue Date: Jul-2002
Publisher: Pergamon-Elsevier Science
Citation: Özarda, Y. vd. (2002). "Free choline and phospholipid-bound choline concentrations in serum and dialysate during peritoneal dialysis in children and adults". Clinical Biochemistry, 35(4), 307-313.
Abstract: Objectives: This study tested whether continuous ambulatory peritoneal dialysis (CAPD) changes free or phospholipid-bound choline concentrations in serum or peritoneal dialysis fluid of patients with end stage renal disease (ESRD). Design and methods: Serum and dialysate choline and phospholipid-bound choline were measured before, during and after 6 h CAPD. Results: Serum choline concentrations were higher in patients with ESRD compared with age-matched controls. CAPD lowered serum choline concentrations significantly although it did not influence phospholipid-bound choline. Choline accumulated in the dialysate, reaching 28.4 +/- 2.7 muM in children and 18.2 +/- 1.4 muM in adults, during six hours CAPD; phospholipid-bound choline increased to 22.9 +/- 2.5 muM and 10.8 +/- 1.4 muM in children and adults, respectively. The total daily loss of choline into the dialysate was 181 +/- 20 mumoles in children and 260 +/- 18 mumoles in adults. Conclusion: CAPD causes a substantial loss of choline into peritoneal dialysates and reduces serum choline concentrations significantly.
URI: https://doi.org/10.1016/S0009-9120(02)00319-3
https://www.sciencedirect.com/science/article/pii/S0009912002003193
http://hdl.handle.net/11452/22452
ISSN: 0009-9120
Appears in Collections:Scopus
Web of Science

Files in This Item:
There are no files associated with this item.
Show full item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.