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http://hdl.handle.net/11452/22499
Başlık: | Brain-derived neurotrophic factor, stress and depression: A minireview |
Yazarlar: | Ozan, Erol Gönül, Ali Saffet Kılıç, Ertuğrul Uludağ Üniversitesi/Tıp Fakültesi. Yuluğ, Burak O-8322-2016 6507583384 |
Anahtar kelimeler: | Depression BDNF Neuroprotection Factor bdnf Hippocampal volume Val66met polymorphism Bipolar disorder Messenger-rna Human-memory Serum Survival Differentiation Association Neurosciences & neurology |
Yayın Tarihi: | 30-Mar-2009 |
Yayıncı: | Pergamon-Elsevier Science |
Atıf: | Yuluğ, B. vd. (2009). "Brain-derived neurotrophic factor, stress and depression: A minireview". Brian Research Bulletin, 78(6), 267-269. |
Özet: | Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family, and is widely expressed in the adult mammalian brain. Besides its well known neuroprotective activity after traumatic brain injury the evidences regarding its activity dependent release by the pathophysiology of major depression are rapidly replicating. Considering the data that stress plays an important role by the development of depression which is characterized with prominent hippocampal cell death, as well as the well known neuroprotective effects of BDNF, we aimed to investigate the link between the BDNF, stress and depression. Thus we prepared a minireview in order to evaluate the neuroprotective role of BDNF by psychiatric disorders which are characterized with prominent neuronal cell death. |
URI: | https://doi.org/10.1016/j.brainresbull.2008.12.002 https://www.sciencedirect.com/science/article/pii/S0361923008004188 http://hdl.handle.net/11452/22499 |
ISSN: | 0361-9230 |
Koleksiyonlarda Görünür: | Scopus Web of Science |
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