1. Açık Erişim@BUU
  2. İndeksli Yayınlar
  3. Web of Science
Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/22650
Başlık: Decreased plasma levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with nonalcoholic fatty liver disease
Yazarlar: Atuğ, Özlen
Yılmaz, Yusuf
Uludağ Üniversitesi/Tıp Fakültesi/Biyokimya Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Endokrinoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Dahiliye Anabilim Dalı.
0000-0003-2467-9356
0000-0003-0463-6818
0000-0003-4518-5283
Ulukaya, Engin
Gül, Özen Öz
Arabul, Mahmut
Gül, Cuma Bülent
Oral, Arzu Yılmaztepe
Aker, Sibel
Dolar, Mahmut Enver
A-7063-2018
AAI-1005-2021
AAG-9177-2021
A-5841-2017
K-5792-2018
22936014300
6602927353
26040787100
15925230900
23988796000
23091316500
12795285000
6602075084
Anahtar kelimeler: Fatty liver
Biological markers
Receptor for advanced glycation endproducts (RAGE)
Enzyme-linked immunosorbent assay
End-products ages
Insulin-resistance
Serum-levels
Rage
Form
Pathogenesis
Galectin-3
Protein
Medical laboratory technology
Yayın Tarihi: Haz-2009
Yayıncı: Pergamon-Elsevier Science
Atıf: Yılmaz, Y. vd. (2009). "Decreased plasma levels of soluble receptor for advanced glycation endproducts (sRAGE) in patients with nonalcoholic fatty liver disease". Clinical Biochemistry, 42(9), 802-807.
Özet: Objectives: Levels of soluble receptor for advanced glycation endproducts (sRAGE) have been linked to several components of the metabolic syndrome. We tested the hypothesis that plasma levels of sRAGE may be associated with non-alcoholic fatty liver disease. Design and methods: We enrolled subjects with definite nonalcoholic steatohepatitis (NASH, n=40), borderline NASH (n=8), simple fatty liver (n=9) and healthy controls (n=14). Plasma levels of sRAGE were measured by ELISA. Results: Concentrations of sRAGE were significantly lower in patients with definite NASH (1080 +/- 392 pg/mL, P<0.01) and borderline NASH (1050 +/- 278 pg/mL, P<0.05) compared to controls (1480 +/- 387 pg/mL). Levels of sRAGE were significantly and inversely correlated with ALT (r=-0.30, P<0.05) and AST (r=-0.23, P<0.05). Conclusion: Plasma levels of sRAGE are significantly reduced in definite and borderline NASH.
URI: https://doi.org/10.1016/j.clinbiochem.2009.02.003
https://www.sciencedirect.com/science/article/pii/S0009912009000848
http://hdl.handle.net/11452/22650
ISSN: 0009-9120
Koleksiyonlarda Görünür:Scopus
Web of Science

Bu öğenin dosyaları:
Bu öğeyle ilişkili dosya bulunmamaktadır.
Tüm Öğe Kaydını Göster İstatistikler


DSpace'deki bütün öğeler, aksi belirtilmedikçe, tüm hakları saklı tutulmak şartıyla telif hakkı ile korunmaktadır.