Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/22785
Başlık: Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Endokrinoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.
0000-0003-0710-5422
0000-0002-1684-1053
Çakır, Esra Deniz Papatya
Mutlu, Fatma Şentürk
Eren, Erdal
Paşa, Aliye Özlem
Sağlam, Halil
Tarım, Ömer
C-7392-2019
AAM-1734-2020
AAH-1155-2021
37003613900
48061357900
36113153400
55270612300
35612700100
6701427186
Anahtar kelimeler: Endocrinology & metabolism
Pediatrics
Testicular adrenal rest tumors
Testicular microlithiasis
Congenital adrenal hyperplasia
Yayın Tarihi: 2012
Yayıncı: Galenos Yayıncılık
Atıf: Çakır, E. D. P. vd. (2012). "Testicular adrenal rest tumors in patients with congenital adrenal hyperplasia". Journal of Clinical Research in Pediatric Endocrinology, 4(2), 94-100.
Özet: Objective: Early diagnosis and treatment of testicular adrenal rest tumors (TART) is important for gonadal functions and fertility protection in boys with congenital adrenal hyperplasia (CAH). In this descriptive study, we investigated the prevalence of TART in boys with 21-hydroxylase deficient (21OHD) CAH followed in our pediatric endocrine clinic. Methods: The study group consisted of 14 male patients with a mean age of 9.6+/-5.1 (range: 0.8-18.3) years. Six (42.9%) of the 14 patients were diagnosed as having salt-wasting type (SW) and eight (57.1%) patients - as having the simple virilizing (SV) form of 21OHD. Mean age at diagnosis was 2.9+/-2.7 (range: 0.03-6.3) years. Two different radiologists performed scrotal ultrasonography. Chronological age, bone age, and anthropometric measurements were evaluated. Serum adrenocorticotropic hormone (ACTH), 17-alpha-hydroxyprogesterone (17OHP) and androstenedione levels were also evaluated in all patients during the follow-up period. Results: Scrotal ultrasonography revealed bilateral TART in two patients (14.3%) and testicular microlithiasis (TM) in four patients (28.6%). One patient had both TART and TM bilaterally. During the follow-up period, the mean serum adrenocorticotropic hormone, 17OHP and androstenedione levels in the total group of patients were 130.0+/-179.1 pg/mL (21.7-726.5), 5.8+/-3.3 ng/mL (0.8-11.4) and 4.3+/-4.1 (0.2-11.0) ng/mL, respectively. Conclusions: Microlithiasis or TART may be frequently encountered during the follow-up of patients with CAH. In order to prevent late complications including infertility, we suggest that ultrasonographic evaluations be performed yearly in all male CAH patients.
URI: https://doi.org/10.4274/jcrpe.563
https://pubmed.ncbi.nlm.nih.gov/22672867/
http://hdl.handle.net/11452/22785
ISSN: 1308-5727
1308-5735
Koleksiyonlarda Görünür:Scopus
Web of Science

Bu öğenin dosyaları:
Dosya Açıklama BoyutBiçim 
Çakır_vd_2012120.53 kBAdobe PDFKüçük resim
Göster/Aç


Bu öğe kapsamında lisanslı Creative Commons License Creative Commons