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http://hdl.handle.net/11452/23172
Başlık: | Effect of benzene on liver functions in rats (Rattus norvegicus) |
Yazarlar: | Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Anabilim Dalı. 0000-0002-6729-7908 Dere, Egemen Arı, Ferda AAG-7012-2021 AAH-5068-2021 6603627015 24376085300 |
Anahtar kelimeler: | Alanine amino transferase Alkaline phosphatase Aspartate amino transferase Benzene Lactate dehydrogenase Microsomal membrane Hl-60 cells Exposure Tissues Phosphorothionate Metabolites Blood Acid Environmental sciences & ecology Rattus Rattus norvegicus Amination Amines Benzene Body fluids Rats Alanine amino transferase Alkaline phosphatase Aspartate Aspartate amino transferase Carcinogenic agents Control groups Intraperitoneally Lactate dehydrogenase Enzymes Benzene Measurement method Phosphatase Physiology Rodent Serum |
Yayın Tarihi: | Tem-2009 |
Yayıncı: | Springer |
Atıf: | Dere, E. ve Arı, F. (2009). "Effect of benzene on liver functions in rats (Rattus norvegicus)". Environmental Monitoring and Assessment, 154(1-4), 23-27. |
Özet: | Rats (Rattus norvegicus) were intraperitoneally injected with a 100 mg kg (-aEuro parts per thousand 1) dosage of benzene, a toxic and carcinogenic agent widely used for industrial purposes. Changes in lactate dehydrogenase (LDH), alkaline phosphatase (ALP), alanine amino transferase (ALT), aspartate amino transferase (AST) activities in serum of rats were investigated at 2, 4, 8, 16, 32, and 64 h following injection. Serum physiological was administered to control group. Activities were measured using autoanalyzer. Benzene caused significant activations in LDH, ALP, and AST activities in the serum at some test hours (p < 0.05). When compared with the control groups, although an increase occurred in ALT activity, it was seem that this increase wasn't significant (p > 0.05). |
URI: | https://doi.org/10.1007/s10661-008-0374-7 https://link.springer.com/article/10.1007%2Fs10661-008-0374-7 http://hdl.handle.net/11452/23172 |
ISSN: | 0167-6369 |
Koleksiyonlarda Görünür: | Scopus Web of Science |
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