Bu öğeden alıntı yapmak, öğeye bağlanmak için bu tanımlayıcıyı kullanınız: http://hdl.handle.net/11452/23428
Başlık: Mediterranean spotted fever: Presentation with pancytopenia
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/ İç Hastalıkları Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.
Özkan, Atilla
Özkalemkaş, Fahir
Ali, Rıdvan
Karadoğan, Serap
Özkocaman, Vildan
Özçelik, Tülay
Tunal, Ahmet
AAG-8495-2021
AAH-1854-2021
9250698600
6601912387
7201813027
9738885800
6603145040
6602797853
Anahtar kelimeler: Hematology
Diseases
Yayın Tarihi: Ağu-2006
Yayıncı: Wiley
Atıf: Özkan, A. vd. (2006). ''Mediterranean spotted fever: Presentation with pancytopenia''. American Journal of Hematology, 81(8), 646-647.
Özet: Mediterranean spotted fever (MSF), Boutonneuse fever, is a tick-borne disease caused by Rickettsia conorii and is endemic in the Mediterranean region. Although MSF is usually a benign infectious disease, unusual manifestations that have been mainly reported in severe forms, typically among elderly patients or those with underlying diseases, complicate the diagnosis. A 39-year-old woman, a resident of Bursa, Turkey, was admitted with a 5-day history of fever, headache, and malaise and a 3-day history of rash. Physical examination showed fever and maculopapular rash involving the trunk, extremities, palms, and soles. Hematological findings were as follows: Hb 10.8 g/dL, WBC 1.7  109/L with 62% polymorphonuclear cells; 9% bands; 20% lymphocytes; 6% metamyelocytes; 3% myelocytes;and platelet count 46.8  109/L. Laboratory studies revealed an elevated CRP (13 mg/L), accelerated ESR (60 mm/h), hypoalbuminemia (2.5 mg/L),and slightly elevated serum aspartate aminotransferase (53 UI/L) and lactate dehydrogenase (386 UI/L). Bone marrow smear showed hypercellular marrow with activation of myeloid cells. After 3 days of hospitalization, we learned that she has a dog in her yard. A ‘‘tache noire,’’ the typicaleschar at the site of the tick bite, was observed on the right inguinal region with more elaborate physical examination. Treatment with doxycycline (200mg/day) was started. Resolution of fever and normalization of haematological findings were observed on the 4th and the 6th days of treatment, respectively.
URI: https://doi.org/10.1002/ajh.20628
https://onlinelibrary.wiley.com/doi/10.1002/ajh.20628
http://hdl.handle.net/11452/23428
ISSN: 0361-8609
Koleksiyonlarda Görünür:Scopus
Web of Science

Bu öğenin dosyaları:
Dosya Açıklama BoyutBiçim 
ajh.20628.pdf197.64 kBAdobe PDFKüçük resim
Göster/Aç


Bu öğe kapsamında lisanslı Creative Commons License Creative Commons