Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/23581
Title: The effects of colloid pre-loading on thromboelastography prior to caesarean delivery: Hydroxyethyl starch 130/0.4 versus succinylated gelatine
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Anesteziyoloji Anabilim Dalı.
0000-0002-6503-8232
0000-0002-3019-581X
Türker, Gürkan
Yılmazlar, Tijen
Başaǧan, Elif Moğol
Gurbet, Alp
Dizman, S.
Günay, H.
AAI-6642-2021
A-7994-2018
7003400116
57212706402
23982134100
35618853300
37103707900
53363383400
Keywords: Research & experimental medicine
Pharmacology & pharmacy
Colloid pre-loading
Thromboelastography
Caesarean section
Spinal anaesthesia
In-vitro
Spinal-anesthesia
Coagulation analysis
Epidural-anesthesia
Impair hemostasis
Ringers solution
Cardiac-surgery
Section
Hemodilution
Hypotension
Issue Date: 2011
Publisher: Sage Publications
Citation: Türker, G. vd. (2011). "The effects of colloid pre-loading on thromboelastography prior to caesarean delivery: Hydroxyethyl starch 130/0.4 versus succinylated gelatine". Journal of International Medical Research, 39(1), 143-149.
Abstract: This prospective, randomized, double-blind study compared the effects on thromboelastography (TEG) of pre-loading with two different colloid fluids prior to spinal anaesthesia for caesarean section. Healthy full-term parturients received either 500 ml 6% hydroxyethyl starch 130/0.4 (HES, n = 25) or 500 ml 4% succinylated gelatine (GEL, n = 25) prior to spinal anaesthesia. TEG parameters including reaction time (r-time), clot formation time (k-time), clot formation rate (alpha-angle) and maximum amplitude (MA) were measured immediately before and after pre-loading. Both groups had significantly shorter r-time and lower MA after pre-loading. The a-angle was significantly decreased after pre-loading with HES but not with GEL. No significant differences in k-time were induced pre-loading. In conclusion, pre-loading with HES or GEL was associated with a mild hypocoagulable effect in healthy parturients presenting for elective caesarean section; however, all TEG parameters in both groups remained within or very close to the normal range after pre-loading.
URI: https://journals.sagepub.com/doi/10.1177/147323001103900115
https://doi.org/10.1177/147323001103900115
http://hdl.handle.net/11452/23581
ISSN: 0300-0605
1473-2300
Appears in Collections:Scopus
Web of Science

Files in This Item:
File Description SizeFormat 
Türker_vd_2011.pdf101.39 kBAdobe PDFThumbnail
View/Open


This item is licensed under a Creative Commons License Creative Commons