Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/23913
Title: End-to-side nerve coaptation is an additional proximal coaptation useful when available
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Plastik ve Rekonstruktif Cerrahi Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Anatomi Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Patoloji Anabilim Dalı.
0000-0003-3368-8123
Özbek, Serhat
Özcan, Mesut
Noyan, Behzat
Kurt, Mustafa Ayberk
Tirelioğlu, Serçin
Bozkurt, Cengiz
Karaca, Kemal
Filiz, Gülaydan
AAH-5441-2021
7005245657
7102067678
6506333172
35603735000
8671609100
6602784313
23988841100
6602693514
Keywords: Surgery
Coaptation
End-to-side neurorrhaphy
Collateral sprouting
Rat
Terminolateral neurorrhaphy
Axonal regeneration
Peripheral-nerve
Motor
Removal
Sheath
Issue Date: Sep-2005
Publisher: Lippincott Williams & Wilkins
Citation: Özbek, S. vd. (2005). "End-to-side nerve coaptation is an additional proximal coaptation useful when available". Annals of Plastic Surgery, 55(3), 281-288.
Abstract: The aim of this experimental study was to evaluate the effects of end-to-side coaptation of the proximal end of a severed nerve to the same intact nerve, in addition to traditional end-to-side coaptation of the distal end, with an aim to use the intact nerve as a nerve conduit in a rat model and to compare the functional and histologic results of this modality to those obtained after nerve grafting and traditional end-to-side nerve coaptation. In group A, a peroneal nerve defect measuring I cm was created in the left hind limb, and a nerve graft I cm long was used to bridge the defect. In group 13, only the distal stump of the peroneal nerve was coapted to the intact tibial nerve. In group C, both ends of the peroneal nerve defect were coapted to the intact tibial nerve in an end-to-side fashion 1.5 cm apart from each other, and in group D, the peroneal nerve defect was left unrepaired. Group E was consisted of nonoperated peroneal nerves that were used to obtain normative data. Although significantly higher myelinated axon densities were observed in groups B and C compared with group A and group E, total number of the myelinated axons was significantly higher only in group C. Peroneal functional index assessments demonstrated that nerve recovery in the peroneal nerve was similar in groups A and C, and both were better than those observed in groups B and D. Collectively, these results suggest that end-to-side coaptation of both ends of a severed nerve to an intact nerve, in case of a nerve defect in this length, may serve as an alternative for nerve grafting.
URI: https://doi.org/10.1097/01.sap.0000171428.47890.13
https://journals.lww.com/annalsplasticsurgery/Fulltext/2005/09000/End_to_Side_Nerve_Coaptation__Is_An_Additional.00013.aspx
http://hdl.handle.net/11452/23913
ISSN: 0148-7043
1536-3708
Appears in Collections:Scopus
Web of Science

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