1. Açık Erişim@BUU
  2. İndeksli Yayınlar
  3. Web of Science
Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/23941
Title: A central link between angiotensinergic and cholinergic systems; role of vasopressin
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Fizyoloji Anabilim Dalı.
0000-0003-0863-1547
İşbil, Büyükcoşkun Naciye
Güleç, Güliz Uyar
Özlük, Kasım
AAH-1692-2021
C-5730-2015
6603128152
6602752303
6602676331
Keywords: Cholinergic system
Ang II
Blood pressure
Heart rate
Intracerebroventricular
V1 antagonist
Pressor
Responses
Release
Injection
Carbachol
Drinking
Brain
Biochemistry & molecular biology
Endocrinology & metabolism
Pharmacology & pharmacy
Issue Date: Sep-2001
Publisher: Elsevier
Citation: İşbil, B. N. vd. (2001). "A central link between angiotensinergic and cholinergic systems; role of vasopressin". Peptides, 22(9), 1415-1420.
Abstract: Participation of central cholinergic system in the effects of intracerebroventricular (i.c.v.) injection of angiotensin II (Ana II) on blood pressure and heart rate was studied in conscious, freely moving rats, Ang II dose-dependently increased blood pressure and decreased heart rate. Both atropine and mecamylamine (i.c.v.) pretreatments prevented the cardiovascular effects of Ana II. Pretreatment with a vasopressin V-1 antagonist also prevented the cardiovascular responses to Ang II. Our data suggest that the central pressor effect of Ang II is mediated in part by central acetylcholine via both muscarinic and nicotinic receptors, and vasopressin participates in this effect through V-1 receptors.
URI: https://www.sciencedirect.com/science/article/pii/S0196978101004788
https://doi.org/10.1016/S0196-9781(01)00478-8
http://hdl.handle.net/11452/23941
ISSN: 0196-9781
Appears in Collections:Scopus
Web of Science

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