Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/24256
Title: HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats
Authors: Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı.
Uludağ Üniversitesi/Veteriner Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.
Mısırlıoğlu, Deniz
Nak, Deniz
Özyiğit, Musa Özgür
Nak, Yavuz
Akkoç, Ahmet
AAR-6478-2021
AAH-2873-2021
AAH-5494-2021
6507455482
9280090000
6507338060
8615464000
55584229300
Keywords: Epidermal-growth-factor
Progesterone-receptor expression
Estrogen
Pyometra
Features
Uterus
Alpha
Dog
Veterinary sciences
Issue Date: Oct-2009
Publisher: Sage Publications
Citation: Mısırlıoğlu, D. vd. (2009). "HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats". Journal of Feline Medicine and Surgery, 11(10), 885-888.
Abstract: The presence of HER-2/neu (c-erbB-2) oncoprotein, oestrogen-alpha. receptor (ER), and progesterone receptor (PR) in hyperplastic endometrial polyps (EPs) of two cats with cystic endometrial hyerplasia-pyometra (CEH-P) complex was investigated. Immunohistochemistry assay for ER, PR and c-erbB-2 oncoprotein in the glandular and stromal tissue of the Ell's was performed. ER and c-erbB-2 immunoreactivity,vas observed in the glandular epithelium of the EPs whereas PR immunoreactivity was detected only in the stromal fibroblasts. The c-erbB-2 oncoprotein may play a role with the ER in the pathogenesis of the hyperplastic EPs, although the role of this oncoprotein in the pathogenesis of EPs has yet to be determined.
URI: https://doi.org/10.1016/j.jfms.2009.04.002
https://journals.sagepub.com/doi/10.1016/j.jfms.2009.04.002
http://hdl.handle.net/11452/24256
ISSN: 1098-612X
Appears in Collections:Scopus
Web of Science

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