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Title: | HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats |
Authors: | Uludağ Üniversitesi/Veteriner Fakültesi/Patoloji Anabilim Dalı. Uludağ Üniversitesi/Veteriner Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı. Mısırlıoğlu, Deniz Nak, Deniz Özyiğit, Musa Özgür Nak, Yavuz Akkoç, Ahmet AAR-6478-2021 AAH-2873-2021 AAH-5494-2021 6507455482 9280090000 6507338060 8615464000 55584229300 |
Keywords: | Epidermal-growth-factor Progesterone-receptor expression Estrogen Pyometra Features Uterus Alpha Dog Veterinary sciences |
Issue Date: | Oct-2009 |
Publisher: | Sage Publications |
Citation: | Mısırlıoğlu, D. vd. (2009). "HER-2/neu (c-erbB-2) oncoprotein in hyperplastic endometrial polyps detected in two cats". Journal of Feline Medicine and Surgery, 11(10), 885-888. |
Abstract: | The presence of HER-2/neu (c-erbB-2) oncoprotein, oestrogen-alpha. receptor (ER), and progesterone receptor (PR) in hyperplastic endometrial polyps (EPs) of two cats with cystic endometrial hyerplasia-pyometra (CEH-P) complex was investigated. Immunohistochemistry assay for ER, PR and c-erbB-2 oncoprotein in the glandular and stromal tissue of the Ell's was performed. ER and c-erbB-2 immunoreactivity,vas observed in the glandular epithelium of the EPs whereas PR immunoreactivity was detected only in the stromal fibroblasts. The c-erbB-2 oncoprotein may play a role with the ER in the pathogenesis of the hyperplastic EPs, although the role of this oncoprotein in the pathogenesis of EPs has yet to be determined. |
URI: | https://doi.org/10.1016/j.jfms.2009.04.002 https://journals.sagepub.com/doi/10.1016/j.jfms.2009.04.002 http://hdl.handle.net/11452/24256 |
ISSN: | 1098-612X |
Appears in Collections: | Scopus Web of Science |
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