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Title: | Ziprasidone and tardive dystonia: A case report and literature review |
Authors: | Uludağ Üniversitesi/Tıp Fakültesi/Psikiyatri Anabilim Dalı. Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı. Turan, Aslı Bahar Akkaya, Cengiz Eker, Salih Saygın Sarandöl, Aslı Karlı, Necdet Q-9477-2019 53664547900 14061855100 14019347700 14020405100 6506587942 |
Keywords: | Pharmacology & pharmacy Psychiatry Ziprasidone Tardive dystonia Schizoaffective disorder Cervical dystonia Botulinum toxin Valproic acid Antipsychotics Clozapine |
Issue Date: | Sep-2011 |
Publisher: | Küre İletişim Grubu |
Citation: | Turan, A. B. vd. (2011). "Ziprasidone and tardive dystonia: A case report and literature review". Klinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology, 21(3), 242-245. |
Abstract: | Ziprasidone and tardive dystonia: a case report and literature review A 40-year-old woman with the diagnosis of schizoaffective disorder had been treated with different typical and atypical antipsychotic drugs since the age of 26. Three months after self-discontinuing her medication, she experienced an exacerbation of her psychotic symptoms, so ziprasidone and valproic acid treatment were started. Six months after initiation of the treatment, tardive dystonia was developed involving the neck region. Discontinuation of ziprasidone produced no benefit; thus clozapine, 75 mg/day, was initiated both for psychotic symptoms and dystonia. Due to lack of improvement in the dystonia and because she suffered from side effects, the dosage of clozapine was decreased to 25 mg/day and botulinum toxin type A treatment was administered. She had partial improvement and repeated injections were planned. Although atypical antipsychotic drugs cause fewer extrapyramidal side effects than typical antipsychotics, we must be cautious when prescribing these drugs because of their disabling side effects. |
URI: | https://doi.org/10.5455/bcp.20110509052149 https://www.tandfonline.com/doi/abs/10.5455/bcp.20110509052149 http://hdl.handle.net/11452/25411 |
ISSN: | 1017-7833 |
Appears in Collections: | Scopus TrDizin Web of Science |
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