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Başlık: Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Kardiyoloji Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı
0000-0002-8974-8837
Eryılmaz, Salih
Aydınlar, Ali
Şentürk, Tunay
Ursavaş, Ahmet
Aydın, Aysel Kaderli
Özdemir, Bülent
AAI-3169-2021
AAI-6632-2021
C-1517-2017
37037269800
6603131517
8342098300
8329319900
36460564300
7004168959
Anahtar kelimeler: Obstructive sleep apnea syndrome
Endothelial dysfunction
Arterial elasticity
Continuous positive airway pressure
Pulse-wave velocity
Endothelial dysfunction
Nitric-oxide
Stiffness
Atherosclerosis
Association
Moderate
CPAP
Cardiovascular system & cardiology
Respiratory system
Yayın Tarihi: Eki-2010
Yayıncı: W B Saunders CO
Atıf: Eryılmaz, S. vd. (2010). "Continuous positive airway pressure therapy improves arterial elasticity in patients with obstructive sleep apnea". Respiratory Medicine, 104(10), 1571-1576.
Özet: Background: Reduced arterial elasticity is an important mediator of accelerated atherogenesis and consequent increased cardiovascular morbidity in obstructive sleep apnea (OSA). The aim of our study was to investigate whether continuous positive airway pressure (CPAP) therapy may improve arterial elasticity in subjects with OSA. Methods: In 44 subjects with OSA, we measured arterial elasticity by applanation tonometry before and after 6 months of treatment with CPAP. Nine OSA+ subjects withdrew from the study. Results: The 35 patients with OSA who completed the 6-month CPAP treatment showed a marked reduction in both the large artery (LAEI, P = 0.001) and small artery (SAEI, P = 0.009) elasticity indices, independent of potential confounders. In OSA+ subjects who withdrew from the study, SAEI and LAEI did not change significantly over time. Conclusions: Six months of CPAP therapy improves arterial elasticity in subjects with OSA.
URI: https://doi.org/10.1016/j.rmed.2010.05.002
https://www.sciencedirect.com/science/article/pii/S0954611110002167
http://hdl.handle.net/11452/27648
ISSN: 0954-6111
1532-3064
Koleksiyonlarda Görünür:Scopus
Web of Science

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