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Başlık: Role of procalcitonin and CRP in diagnosis and follow-up of neonatal sepsis
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Pediatri Bölümü.
Köksal, Nilgün
Harmancı, Ramazan
Çetinkaya, Merih
Hacımustafaoğlu, Mustafa
7003323615
16229945500
23994946300
6602154166
Anahtar kelimeler: C-reactive protein
Newborn
Procalcitonin
Sepsis
Serum procalcitonin
Increase
Count
Yayın Tarihi: 2007
Yayıncı: Türkiye Milli Pediatri Derneği
Atıf: Köksal, N. vd. (2007). "Role of procalcitonin and CRP in diagnosis and follow-up of neonatal sepsis". Turkish Journal of Pediatrics, 49(1), 21-29.
Özet: We aimed to investigate the role of procalcitonin in the diagnosis and follow-up of neonatal sepsis, and to compare it with C-reactive protein (CRP) in this context. Between April and October 2002, a total of 67 neonates were randomly recruited into the study and were divided into four groups as: those with highly probable sepsis (group 1), probable, sepsis (group 2), possible sepsis (group 3), and no sepsis (group 4; controls). When the initial procalcitonin levels of the groups were compared, the results were statistically significant (p < 0.05) except for the comparison between groups 3 and 4 (p > 0.05). When the initial CRP levels were compared between the groups, the levels measured in groups 1 and 2 were significantly higher than the levels measured in groups 3 and 4 (p < 0.05). In addition, the decreasing levels in procalcitonin were statistically more significant than the decreasing levels in CRP in showing the response to antibiotic treatment (p < 0.01 and p < 0.05, respectively). In conclusion, serum procalcitonin levels seemed to be superior to serum CRP levels in terms of early diagnosis of neonatal sepsis, in detecting the severity of the illness, and in evaluation of the response to antibiotic treatment.
URI: https://www.turkishjournalpediatrics.org/uploads/pdf_TJP_377.pdf
http://hdl.handle.net/11452/28557
ISSN: 0041-4301
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

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