Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29258
Title: Successful spontaneous pregnancy in a patient with rectal carcinoma treated with pelvic radiotherapy and concurrent chemotherapy: The unique role of laparoscopic lateral ovary transposition
Authors: Uludağ Üniversitesi/Tıp Fakültesi/Onkoloji Bölümü.
Uludağ Üniversitesi/Tıp Fakültesi/Kadın Hastalıkları ve Doğum Anabilim Dalı.
0000-0003-1637-910X
Kurt, Meral
Uncu, Gürkan
Çetintaş, Sibel Kahraman
Küçük, Nesrin
Güler, Selver
Özkan, Lütfü
AAA-3961-2020
AAA-7047-2020
8843050600
6603716169
6505881756
19035021700
57212661524
55915679400
Keywords: Laparoscopic ovary transposition
Pelvic radiotherapy
Rectal carcinoma
Oncology
Obstetrics & gynecology
Abdominal irradiation
Human oocyte
Childhood
Radiosensitivity
Failure
Issue Date: 2007
Publisher: Imr Press
Citation: Kurt, M. vd. (2007). "Successful spontaneous pregnancy in a patient with rectal carcinoma treated with pelvic radiotherapy and concurrent chemotherapy: The unique role of laparoscopic lateral ovary transposition". European Journal of Gynaecological Oncology, 28(5), 408-410.
Abstract: Concurrent administration of external beam pelvic radiotherapy (RT) and chemotherapy (CT) is an effective treatment modality for rectal cancer. In adults in reproductive age, one of the most important side-effects resulting from this treatment is gonadal toxicity. Fortunately, it is possible to protect the ovaries by transporting them out of the RT area through lateral ovary transposition (LOT), as a minimally invasive method, which is performed before the application of RT. A 24-year-old female was diagnosed as having rectal adenocarcinoma in May 2003, and she was scheduled to receive adjuvant 5-fluorouracil-based CT followed by concurrent chemoradiotherapy (CRT). Before the onset of the adjuvant treatments, laparoscopic LOT was performed, and the patient was followed-up appropriately. Although amenorrhea developed during the CRT, the menstrual cycle of the patient resumed without performing any medical treatment eight weeks after the completion of the CRT. In July 2005, the patient became pregnant spontaneously with no local or systemic recurrences of rectal cancer. The present case shows that ovarian functions can be successfully protected in rectal cancer patients receiving RT by laparoscopic LOT, and by modifying the RT fields.
URI: http://hdl.handle.net/11452/29258
ISSN: 0392-2936
Appears in Collections:PubMed
Scopus
Web of Science

Files in This Item:
There are no files associated with this item.


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.