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Başlık: Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkey
Yazarlar: Çiftçi, Ergin
Tuygun, Nilden
Özdemir, Halil
Tezer, Hasan
Şensoy, Gülnar
Devrim, İlker
Dalgıç, Nazan
Kara, Ateş
Turgut, Mehmet
Tapısız, Anıl
Keser, Melike
Bayram, Nuri
Kocabaş, Emine
Dinleyici, Ener Çağrı
Özen, Metehan
Soysal, Ahmet
Kuyucu, Necdet
Tanır, Gönül
Çelikel, Elif
Belet, Nursen
Evren, Gültaç
Aytaç, Didem Büyüktaş
Cengiz, Ali Bülent
Canoz, Perihan Yasemen
Derinoz, Oksan
İnce, Erdal
Hacımustafaoğlu, Mustafa
Anıl, Murat
Özgür, Özlem
Kuzdan, Canan
Özaydin, Eda
Aşılıoğlu, Nazik
Dizdarer, Ceyhun
Ceyhan, Mehmet
Bucak, İbrahim Hakan
Kendirli, Tanıl
Yakut, Halil İbrahim
Fisgin, Tunç
Unal, Nurettin
Altındağ, Hakan
Kılınç, Ayse Ayzit
Zohre, Seray Umut
Elhan, Atilla Halil
Doğru, Ülker
Uludağ Üniversitesi/Tıp Fakültesi/Çocuk Enfeksiyon Hastalıkları Anabilim Dalı.
Çelebi, Solmaz
7006095295
Anahtar kelimeler: Infectious diseases
Children
Influenza A
H1N1
Mortality
UK
Yayın Tarihi: Ara-2011
Yayıncı: Informa Healthcare
Atıf: Çiftçi, E. vd.(2011). "Clinical and epidemiological features of Turkish children with 2009 pandemic influenza A (H1N1) infection: Experience from multiple tertiary paediatric centres in Turkey".Scandinavian Journal of Infectious Diseases, 43(11-12), 923-929.
Özet: Background: In April 2009 a novel strain of human influenza A, identified as H1N1 virus, rapidly spread worldwide, and in early June 2009 the World Health Organization raised the pandemic alert level to phase 6. Herein we present the largest series of children who were hospitalized due to pandemic H1N1 infection in Turkey. Methods: We conducted a retrospective multicentre analysis of case records involving children hospitalized with influenza-like illness, in whom 2009 H1N1 influenza was diagnosed by reverse-transcriptase polymerase chain reaction assay, at 17 different tertiary hospitals. Results: A total of 821 children with 2009 pandemic H1N1 were hospitalized. The majority of admitted children (56.9%) were younger than 5 y of age. Three hundred and seventy-six children (45.8%) had 1 or more pre-existing conditions. Respiratory complications including wheezing, pneumonia, pneumothorax, pneumomediastinum, and hypoxemia were seen in 272 (33.2%) children. Ninety of the patients (11.0%) were admitted or transferred to the paediatric intensive care units (PICU) and 52 (6.3%) received mechanical ventilation. Thirty-five children (4.3%) died. The mortality rate did not differ between age groups. Of the patients who died, 25.7% were healthy before the H1N1 virus infection. However, the death rate was significantly higher in patients with malignancy, chronic neurological disease, immunosuppressive therapy, at least 1 pre-existing condition, and respiratory complications. The most common causes of mortality were pneumonia and sepsis. Conclusions: In Turkey, 2009 H1N1 infection caused high mortality and PICU admission due to severe respiratory illness and complications, especially in children with an underlying condition.
URI: https://doi.org/10.3109/00365548.2011.598872
https://www.tandfonline.com/doi/full/10.3109/00365548.2011.598872
http://hdl.handle.net/11452/29436
ISSN: 0036-5548
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

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