Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29754
Title: Antioxidant and antimicrobial potential, and HPLC analysis of stictic and usnic acids of three Usnea species from Uludag mountain (Bursa, Turkey)
Authors: Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Biyoloji Bölümü.
Bursa Uludağ Üniversitesi/Fen-Edebiyat Fakültesi/Kimya Bölümü.
Uludağ Üniversitesi/Veteriner Fakültesi/Farmakoloji ve Toksikoloji Anabilim Dalı/Moleküler Farmakoloji Laboratuvarı.
0000-0001-8196-2065
0000-0003-1508-0181
0000-0003-1508-0181
0000-0002-9381-0410
Oran, Seyhan
Şahin, Saliha
Şahintürk, Pınar
Öztürk, Şule
Demir, Cevdet
AAH-5039-2021
AAH-2892-2021
AFR-1890-2022
AAD-7322-2019
ABA-2005-2020
14067648200
15027401600
55342852700
7004555373
7003565902
Keywords: Pharmacology & pharmacy
Stictic acid
Usnea fulvoreagens
Usnea filipendula
Usnea intermedia
Usnic acid
Secondary metabolites
Hypogymnia-physodes
Phenolic content
Lichens
Extracts
Constituents
Issue Date: Jan-2015
Publisher: Shaheed Beheshti
Citation: Oran, S. vd. (2016). "Antioxidant and antimicrobial potential, and HPLC analysis of stictic and usnic acids of three Usnea species from Uludag mountain (Bursa, Turkey)". Iranian Journal of Pharmaceutical Research, 15(2), 527-535.
Abstract: In this study, antioxidant and antimicrobial potentials of Usnea intermedia, U. filipendula, and U. fulvoreagens and their stictic and usnic acid contents were investigated. Antioxidant activity and total phenolic contents were evaluated in acetone, ethanol, and methanol extracts of these three species. Antioxidant activity was measured by ABTS [2,2'-azino-bis(3-ethylbenzothiazoline- 6-sulphonic acid)] method and total phenolic contents were measured by Folin-Ciocalteu method. High-performance liquid chromatography (HPLC) was used for the determination of lichen acids. It can be concluded from stictic and usnic acids contents that the order of solvent efficiency is acetone > ethanol > methanol and acetone > methanol > ethanol, respectively. Broth microdilution method was performed to determine the minimum inhibitory concentration (MIC) of the methanol extracts of three Usnea species. The MIC values of all the extracts ranged from 64 mu g/mL to 512 mu g/mL for all the bacterial strains that were tested in this study, and all the Fluoro quinolone-resistant Escherichia coli isolates (except for E101) were sensitive to the methanol extracts of the three Usnea species. This paper is the first study to determine the stictic acid content in U. intermedia and U. filipendula. Our findings indicate that these three Usnea species could be used as antioxidant and antimicrobial agents.
URI: https://pubmed.ncbi.nlm.nih.gov/27642324/
http://hdl.handle.net/11452/29754
ISSN: 1735-0328
1726-6890
Appears in Collections:Scopus
Web of Science

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