Please use this identifier to cite or link to this item: http://hdl.handle.net/11452/29807
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dc.date.accessioned2022-12-12T08:17:19Z-
dc.date.available2022-12-12T08:17:19Z-
dc.date.issued2016-04-15-
dc.identifier.citationDilektaşlı, A. G. vd. (2016). "Catheter-directed therapy in acute pulmonary embolism with right ventricular dysfunction: A promising modality to provide early hemodynamic recovery". Medical Science Monitor, 22, 1265-1273.en_US
dc.identifier.issn1643-3750-
dc.identifier.urihttps://doi.org/10.12659/MSM.897617-
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835153/-
dc.identifier.urihttps://medscimonit.com/abstract/index/idArt/897617-
dc.identifier.urihttp://hdl.handle.net/11452/29807-
dc.description.abstractBackground: Catheter-directed therapy (CDT) for pulmonary embolism (PE) is considered as an alternative to systemic thrombolysis (ST) in patients with hemodynamically unstable acute PE who are considered at high bleeding risk for ST. We aimed to evaluate the efficacy and safety of CDT in the management of acute PE with right ventricular dysfunction (RVD). The primary outcomes were mortality, clinical success, and complications. Secondary outcomes were change in hemodynamic parameters in the first 24 hours following the procedure. Material/Methods: Medical records of consecutive patients diagnosed as having acute massive or submassive PE with accompanying RVD treated by immediate CDT at our institution from January 2007 to January 2014 were reviewed. Patient characteristics, mortality, achievement of clinical success, and minor and major bleeding complications were analyzed in the overall study group, as well as massive vs. submassive PE subgroups. Change in hemodynamic parameters in the second, eighth, and 24th hours after the CDT procedure were also analyzed. Results: The study included 15 consecutive patients (M/F=10/5) with a mean age of 54.2 +/- 16.6 years who underwent immediate CDT. Nine of the patients had submassive PE, and 6 had massive PE. In-hospital mortality rate was 13.3% (95% CI, 0.04-0.38). One major, but not life-threatening, bleeding episode was evident in the whole group. Hemodynamic parameters were stabilized and clinical success was achieved in 14/15 (93.3%; 95% CI, 70.2-98.8) of the patients in the first 24 hours. Notably, the hemodynamic recovery was significantly evident in the first 8 hours after the procedure. Conclusions: CDT is a promising treatment option for patients with acute PE with RVD with no fatal bleeding complication. In experienced centers, CDT should be considered as a first-line treatment for patients with acute PE and RVD and contraindications for ST, with the advantage of providing early hemodynamic recovery.en_US
dc.language.isoenen_US
dc.publisherInt Scientific Informationen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectResearch & experimental medicineen_US
dc.subjectMechanical thrombolysisen_US
dc.subjectPulmonary embolismen_US
dc.subjectThrombolytic therapyen_US
dc.subjectRheolytic thrombectomyen_US
dc.subjectManagementen_US
dc.subjectFragmentationen_US
dc.subjectThrombolysisen_US
dc.subjectFibrinolysisen_US
dc.subjectEmbolectomyen_US
dc.subjectOutcomesen_US
dc.subjectPatienten_US
dc.subject.meshAdulten_US
dc.subject.meshAgeden_US
dc.subject.meshCatheterizationen_US
dc.subject.meshEndovascular proceduresen_US
dc.subject.meshFemaleen_US
dc.subject.meshHemodynamicsen_US
dc.subject.meshHemorrhageen_US
dc.subject.meshHospital mortalityen_US
dc.subject.meshHumansen_US
dc.subject.meshMaleen_US
dc.subject.meshMiddle ageden_US
dc.subject.meshPulmonary embolismen_US
dc.subject.meshRetrospective studiesen_US
dc.subject.meshRisk factorsen_US
dc.subject.meshThrombolytic therapyen_US
dc.subject.meshTreatment outcomeen_US
dc.subject.meshVentricular dysfunction, righten_US
dc.titleCatheter-directed therapy in acute pulmonary embolism with right ventricular dysfunction: A promising modality to provide early hemodynamic recoveryen_US
dc.typeArticleen_US
dc.identifier.wos000374178800002tr_TR
dc.identifier.scopus2-s2.0-84964290541tr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergitr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Göğüs Hastalıkları Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Radyoloji Anabilim Dalı.tr_TR
dc.contributor.departmentUludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Anabilim Dalı.tr_TR
dc.contributor.orcid0000-0002-9027-1132tr_TR
dc.contributor.orcid0000-0002-6375-1472tr_TR
dc.contributor.orcid0000-0003-3604-8826tr_TR
dc.contributor.orcid0000-0003-0297-846Xtr_TR
dc.identifier.startpage1265tr_TR
dc.identifier.endpage1273tr_TR
dc.identifier.volume22tr_TR
dc.relation.journalMedical Science Monitoren_US
dc.contributor.buuauthorDilektaşlı, Aslı Görek-
dc.contributor.buuauthorÇetinoğlu, Ezgi Demirdoğen-
dc.contributor.buuauthorAcet, Nilüfer Aylin-
dc.contributor.buuauthorErdoğan, Cüneyt-
dc.contributor.buuauthorUrsavaş, Ahmet-
dc.contributor.buuauthorÖzkaya, Güven-
dc.contributor.buuauthorCoşkun, Funda-
dc.contributor.buuauthorKaradağ, Mehmet-
dc.contributor.buuauthorEge, Ercüment-
dc.contributor.researcheridAAG-8744-2021tr_TR
dc.contributor.researcheridZ-1424-2019tr_TR
dc.contributor.researcheridAAD-1271-2019tr_TR
dc.contributor.researcheridA-4421-2016tr_TR
dc.contributor.researcheridAAI-3169-2021tr_TR
dc.identifier.pubmed27081754tr_TR
dc.subject.wosMedicine, research & experimentalen_US
dc.indexed.wosSCIEen_US
dc.indexed.scopusScopusen_US
dc.indexed.pubmedPubMeden_US
dc.contributor.scopusid36466376600tr_TR
dc.contributor.scopusid57189524206tr_TR
dc.contributor.scopusid56507253300tr_TR
dc.contributor.scopusid8293835700tr_TR
dc.contributor.scopusid8329319900tr_TR
dc.contributor.scopusid16316866500tr_TR
dc.contributor.scopusid21734137500tr_TR
dc.contributor.scopusid6601970351tr_TR
dc.contributor.scopusid6701341320tr_TR
dc.subject.scopusLung Embolism; Embolectomy; Blood Clot Lysisen_US
dc.subject.emtreeAdulten_US
dc.subject.emtreeArterial oxygen saturationen_US
dc.subject.emtreeArticleen_US
dc.subject.emtreeBleedingen_US
dc.subject.emtreeBlood pressure monitoringen_US
dc.subject.emtreeClinical articleen_US
dc.subject.emtreeComputer assisted tomographyen_US
dc.subject.emtreeElectronic medical recorden_US
dc.subject.emtreeFemaleen_US
dc.subject.emtreeGuide wireen_US
dc.subject.emtreeHeart ventricle functionen_US
dc.subject.emtreeHemodynamicsen_US
dc.subject.emtreeHumanen_US
dc.subject.emtreeLung angiographyen_US
dc.subject.emtreeLung artery pressureen_US
dc.subject.emtreeLung embolismen_US
dc.subject.emtreeMaleen_US
dc.subject.emtreeMechanical thrombectomyen_US
dc.subject.emtreeMiddle ageden_US
dc.subject.emtreeMortalityen_US
dc.subject.emtreeRetrospective studyen_US
dc.subject.emtreeTransthoracic echocardiographyen_US
dc.subject.emtreeVentriculostomy catheteren_US
dc.subject.emtreeAgeden_US
dc.subject.emtreeCatheterizationen_US
dc.subject.emtreeEndovascular surgeryen_US
dc.subject.emtreeFibrinolytic therapyen_US
dc.subject.emtreeHeart right ventricle functionen_US
dc.subject.emtreeHemodynamicsen_US
dc.subject.emtreeHemorrhageen_US
dc.subject.emtreeHospital mortalityen_US
dc.subject.emtreePathophysiologyen_US
dc.subject.emtreeProceduresen_US
dc.subject.emtreePulmonary embolismen_US
dc.subject.emtreeRisk factoren_US
dc.subject.emtreeTreatment outcomeen_US
Appears in Collections:Scopus
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