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Başlık: Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study
Yazarlar: Bursa Uludağ Üniversitesi/Tıp Fakültesi/Nöroloji Anabilim Dalı.
Bakar, Mustafa
EKN-8251-2022
26643051200
Anahtar kelimeler: Cerebrovascular disease
Epilepsy
Early seizure
Cerebral venous sinus thrombosis
Risk-factors
Vein
Puerperium
Pregnancy
Neurosciences & neurology
Yayın Tarihi: 28-Şub-2020
Yayıncı: W B Saunders
Atıf: Uluduz, D. vd. (2020). "Epileptic seizures in cerebral venous sinus thrombosis: Subgroup analysis of VENOST study". Seizure, 78, 113-117.
Özet: Purpose: The aim of this study is to evaluate the presence and prognostic impact of early seizures in cerebral venous sinus thrombosis patients (CVST). Method: VENOST is a retrospective and prospective national multicenter observational study. CVST patients with or without epileptic seizures (ES) were analyzed and compared in terms of demographic and imaging data, causative factors, clinical variables, and prognosis in a total of 1126 patients. Results: The mean age of the patients in the ES group was 39.73 +/- 12.64 and 40.17 +/- 14.02 years in the non-ES group (p > 0.05). Epileptic seizures were more common (76.6 %) in females (p < 0.001). Early ES occurred in 269 of 1126 patients (23.9 %). Epileptic seizures mainly presented in the acute phase (71.4 %) of the disease (p < 0.001). Majority of these (60.5 %) were in the first 24 h of the CVST. The most common neurological signs were focal neurologic deficits (29.9 %) and altered consciousness (31.4 %) in the ES group. Superior sagittal sinus (SSS) and cortical veins (CV) involvement were the most common sites of thrombosis and the mostly related etiology were found puerperium in seizure group (30.3 % vs 13.9 %). Patients with seizures had worse outcome in the first month of the disease (p < 0.001) but these did not have any influence thereafter. Conclusions: In this largest CVST cohort (VENOST) reported female sex, presence of focal neurological deficits and altered consciousness, thrombosis of the SSS and CVs, hemorrhagic infarction were risk factors for ES occurrence in patients with CVST.
Açıklama: Çalışmada 38 yazar bulunmaktadır. Bu yazarlardan sadece Bursa Uludağ Üniversitesi mensuplarının girişleri yapılmıştır.
URI: https://doi.org/10.1016/j.seizure.2020.02.017
https://www.sciencedirect.com/science/article/pii/S1059131120300595
http://hdl.handle.net/11452/30072
ISSN: 1059-1311
1532-2688
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

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