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Başlık: Chandrakala SFCR The value of spectrophotometric intracutaneous analysis in the noninvasive diagnosis of nonmelanoma skin cancers
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Dermatoloji Anabilim Dalı.
0000-0002-0193-1128
Hacıoǧlu, Şenay
Sarıcaoğlu, Hayriye
Başkan, Emel Bülbül
Uner, S. I.
Aydoĝan, Kenan
Tunalı, Şükran
AAH-6216-2021
36196495300
6603722836
6602518817
55914302400
9739755800
7004191748
Anahtar kelimeler: Dermatology
Basal-cell carcinoma
Optical coherence tomograph
In-vivo
Lesions
Microscopy
Dermoscopy
Accuracy
Yayın Tarihi: 18-Haz-2013
Yayıncı: Wiley
Atıf: Hacıoǧlu, S. vd. (2013). "Chandrakala SFCR The value of spectrophotometric intracutaneous analysis in the noninvasive diagnosis of nonmelanoma skin cancers". Clinical and Experimental Dermatology, 38(5), 464-469.
Özet: Background. Spectrophotometric intracutaneous analysis (SIAscopy) is a recently introduced, noninvasive, rapid and practical method for monitoring pigmented lesions, which calculates the amount of collagen, melanin and haemoglobin deep in the papillary dermis. Aim. To evaluate the value of SIAscopy in the diagnosis of nonmelanoma skin cancers (NMSC). Methods. In total, 80 lesions of 76 patients were clinically evaluated by the first investigator, and the data recorded. Eight months after the clinical evaluation, all lesions were evaluated again by the same investigator, using images (SIAgraphs) obtained by the SIAscope. All SIAgraphs were also evaluated by a second investigator, and all dermatoscopic images by a third, independently of each other. All diagnoses were compared with histopathological diagnoses. Results. The clinical diagnosis was calculated to have a sensitivity of 79% and specificity of 84%. The SIAscopic diagnoses of the first and second investigators had a sensitivity of 55% and 93%, and a specificity of 88% and 53%, respectively, while the dermatoscopic diagnoses of the third investigator had a sensitivity of 86% and specificity of 80%. There was no statistical accordance between the first and second investigators according to the accuracy of SIAscopic diagnoses (P<0.01). The area under the curve for the receiver operator characteristic was 0.82 for clinical diagnosis, 0.73 and 0.80 for the SIAscopic evaluation of the first and the second investigators, respectively, and 0.87 for the dermatoscopic evaluation of the third investigator. Conclusions. Our findings show that dermatoscopic findings are more valuable than SIAscopic and clinical findings for the noninvasive diagnosis of NMSC. We consider that SIAscopy makes no substantial contribution towards the differential diagnosis of NMSC.
URI: https://doi.org/10.1111/j.1365-2230.2012.04460.x
https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2230.2012.04460.x
http://hdl.handle.net/11452/30178
ISSN: 0307-6938
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

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