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http://hdl.handle.net/11452/30722
Başlık: | Comprehensive assessment of candidate genes associated with fattening performance in Holstein-Friesian bulls |
Yazarlar: | Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Zootekni ve Hayvan Besleme Bölümü. 0000-0003-2758-5945 0000-0003-2382-1330 Ardıçlı, Sena Şamlı, Hale Vatansever, Buse Soyudal, Bahadır Dinçel, Deniz Balcı, Faruk AAM-4361-2020 AAH-6488-2021 O-3394-2019 AAH-6192-2021 56607305700 6507670789 57203938885 56607355300 56607385000 16062981700 |
Anahtar kelimeler: | Agriculture Quantitative trait loci Meat quality traits Single nucleotide polymorphisms Growth-hormone receptor Estimated breeding values Bovine leptin gene Carcass characteristics Beef-cattle Fabp4 gene Snp marker |
Yayın Tarihi: | 10-Oca-2019 |
Yayıncı: | Copernicus Publications |
Atıf: | Ardıçlı, S. vd. (2019). ''Comprehensive assessment of candidate genes associated with fattening performance in Holstein-Friesian bulls''. Archives Animal Breeding, 62(1), 9-32. |
Özet: | The objective of this study was to determine the association of single nucleotide polymorphisms (SNPs) in selected candidate genes with fattening performance traits in a commercial cattle herd. Fifteen SNPs in 12 candidate genes (LEP, FABP4, DGAT1, TG, IGF1, IGF1R, MYF5, LGB, CAPN1, CAST, GHR, and OLR1) were evaluated in 296 purebred Holstein-Friesian bulls using PCR-RFLP (polymerase chain reaction - restriction fragment length polymorphism). Associations between each segregating SNP and genetic merit for fattening performance were quantified using linear mixed models. Traits included in the study were fattening period, final weight, dry matter intake, feed conversion rate, and average daily weight gain. Apart from the general determination of the above-mentioned traits, each trait was evaluated based on the fattening periods between five selected target body weights (W1 = 100 kg, W2 = 200 kg, W3 = 300 kg, W4 = 400 kg, W5 = 450 kg). All markers with the exception of CAPN1 530, IGF1R, TG, and DGAT1 were associated with at least one of the traits. Furthermore, novel associations were observed for LEP x GHR, IGF1 x LEP, FABP4 3691 x FABP4 2834, and FAP4 3533 x LEP interactions. The results of this study confirm some previously reported associations. Moreover, novel associations have been identified, which may be incorporated into breeding programs to improve fattening performance. |
URI: | https://doi.org/10.5194/aab-62-9-2019 https://aab.copernicus.org/articles/62/9/2019/aab-62-9-2019.pdf http://hdl.handle.net/11452/30722 |
ISSN: | 0003-9438 2363-9822 |
Koleksiyonlarda Görünür: | PubMed Scopus Web of Science |
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