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Başlık: Comprehensive assessment of candidate genes associated with fattening performance in Holstein-Friesian bulls
Yazarlar: Bursa Uludağ Üniversitesi/Veteriner Fakültesi/Zootekni ve Hayvan Besleme Bölümü.
0000-0003-2758-5945
0000-0003-2382-1330
Ardıçlı, Sena
Şamlı, Hale
Vatansever, Buse
Soyudal, Bahadır
Dinçel, Deniz
Balcı, Faruk
AAM-4361-2020
AAH-6488-2021
O-3394-2019
AAH-6192-2021
56607305700
6507670789
57203938885
56607355300
56607385000
16062981700
Anahtar kelimeler: Agriculture
Quantitative trait loci
Meat quality traits
Single nucleotide polymorphisms
Growth-hormone receptor
Estimated breeding values
Bovine leptin gene
Carcass characteristics
Beef-cattle
Fabp4 gene
Snp marker
Yayın Tarihi: 10-Oca-2019
Yayıncı: Copernicus Publications
Atıf: Ardıçlı, S. vd. (2019). ''Comprehensive assessment of candidate genes associated with fattening performance in Holstein-Friesian bulls''. Archives Animal Breeding, 62(1), 9-32.
Özet: The objective of this study was to determine the association of single nucleotide polymorphisms (SNPs) in selected candidate genes with fattening performance traits in a commercial cattle herd. Fifteen SNPs in 12 candidate genes (LEP, FABP4, DGAT1, TG, IGF1, IGF1R, MYF5, LGB, CAPN1, CAST, GHR, and OLR1) were evaluated in 296 purebred Holstein-Friesian bulls using PCR-RFLP (polymerase chain reaction - restriction fragment length polymorphism). Associations between each segregating SNP and genetic merit for fattening performance were quantified using linear mixed models. Traits included in the study were fattening period, final weight, dry matter intake, feed conversion rate, and average daily weight gain. Apart from the general determination of the above-mentioned traits, each trait was evaluated based on the fattening periods between five selected target body weights (W1 = 100 kg, W2 = 200 kg, W3 = 300 kg, W4 = 400 kg, W5 = 450 kg). All markers with the exception of CAPN1 530, IGF1R, TG, and DGAT1 were associated with at least one of the traits. Furthermore, novel associations were observed for LEP x GHR, IGF1 x LEP, FABP4 3691 x FABP4 2834, and FAP4 3533 x LEP interactions. The results of this study confirm some previously reported associations. Moreover, novel associations have been identified, which may be incorporated into breeding programs to improve fattening performance.
URI: https://doi.org/10.5194/aab-62-9-2019
https://aab.copernicus.org/articles/62/9/2019/aab-62-9-2019.pdf
http://hdl.handle.net/11452/30722
ISSN: 0003-9438
2363-9822
Koleksiyonlarda Görünür:PubMed
Scopus
Web of Science

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