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Başlık: Aspirin resistance in patients presenting to the emergency department
Yazarlar: Uludağ Üniversitesi/Tıp Fakültesi/Acil Tıp Anabilim Dalı.
Uludağ Üniversitesi/Tıp Fakültesi/Biyoistatistik Bölümü.
0000-0003-2271-5659
Köse, Ataman
Köksala, Özlem
Armağan, Erol
Sığırlı, Deniz
Özdemir, Fatma
Akköse, Sule
AAM-7896-2020
AAK-8332-2020
AAA-7472-2021
AAH-8846-2021
L-7334-2015
55792812100
55792424600
55792577900
55792509300
57214275466
55792876000
Anahtar kelimeler: General & internal medicine
Emergency department
Aspirin resistance
Renal failure
Pulse pressure
Aspirin intake time
Coronary
Frequency
Nonresponder
Prevalence
Disease
Yayın Tarihi: 2013
Yayıncı: Carbone Editore
Atıf: Köse, A. vd. (2013). “Aspirin resistance in patients presenting to the emergency department”. Acta Medica Mediterranea, 29(2), 247-253.
Özet: Introduction: The effect of aspirin is not the same for all patients and some patients can be resistant. Few emergency department (ED) studies have prospectively determined the rate of aspirin resistance in patients presenting to the ED and the most of them consider only specific group of patients. We aimed to evaluate the relation between clinical and laboratory parameters with aspirin resistance in patients presenting to the ED Methods: Using the bed-side point-of-care VerifyNow Aspirin assay (Accumetrics, San Diego, Calif), we sought to determine the rate of aspirin resistance in patients presenting to the ED with any complaint. Results: A total of 97 patients were included in this study. Aspirin resistance was found in 29 (29.9%) of them. There were not any significant differences in age, sex, drug usage, platelet count, ECG changes, heart rate, systolic, or diastolic blood pressure measures between the aspirin-resistant and aspirin-sensitive patients. In addition, patients' aspirin sensitivity and aspirin resistance did not differ significantly with regard to clinic results and diagnoses in the ED. However, patients with renal failure had significantly more aspirin resistance than other patients (p=0.007). Besides, the relationship between aspirin intake <30 time, pulse pressure and aspirin resistance were found out significant. Conclusion: To the best of our knowledge, this second current report of aspirin resistance in patients presenting to the ED pointed-out its presence in 29.9% of patients. In aspirin resistance, renal failure, pulse pressure and aspirin intake time were determined as important factors.
URI: http://hdl.handle.net/11452/32811
ISSN: 0393-6384
2283-9720
Koleksiyonlarda Görünür:Scopus
Web of Science

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